Effectiveness and safety of Chinese herbal medicine formula Gualou Xiebai Banxia (GLXBBX) decoction for the treatment of stable angina pectoris: Protocol for a systematic review

Medicine
Mingtai ChenZhong Zhang

Abstract

Stable angina pectoris (SAP) is one of the most common symptoms of coronary heart disease. Chinese herbal medicine (CHM) has been used to treat SAP increasingly due to its less side effects. The subject of this study is to explore the effectiveness and safety of Gualou Xiebai Banxia (GLXBBX) decoction as a kind of CHM for SAP. A systematic literature search for articles up to June 2018 will be performed in following electronic databases: PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure, Chinese Scientific Journals Database, Chinese Biomedical Database, Chinese Biomedical Literature Service System (SinoMed), and Wanfang Database. Inclusion criteria are randomized controlled trials of modified GLXBBX decoction applied on patients with SAP. The primary outcome measures will be coronary heart disease-related clinical evaluation (frequency of acute attack angina, severity of angina pectoris, electrocardiographic changes, and amount of nitroglycerin) and adverse events. RevMan 5.3 software will be used for data synthesis, sensitivity analysis, metaregression, subgroup analysis, and risk of bias assessment. A funnel plot will be developed to evaluate reporting bias and Egger tests will be used to assess fu...Continue Reading

References

Feb 7, 2003·Journal of the American College of Cardiology·Raymond J GibbonsUNKNOWN American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable An
Jan 29, 2013·Current Opinion in Pharmacology·Thomas Münzel, Tommaso Gori
Sep 25, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Yulan RenFanrong Liang
Dec 10, 2015·Australian Prescriber·Yong WeeNicholas Bett
Jan 19, 2016·Journal of Integrative Medicine·Qing JiShi-bing Su
Oct 25, 2016·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Jianchun HuangXiaolong Kong

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Methods Mentioned

BETA
pharmacotherapy

Software Mentioned

RevMan
EndNote X7

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