Effectiveness and safety of rivaroxaban in a cohort of 142 patients with nonvalvular atrial fibrillation treated with rivaroxaban for the prevention of stroke

Future Cardiology
Juan José Cerezo-ManchadoJosé María Moraleda-Jiménez

Abstract

To evaluate the clinical profile and effectiveness/safety of patients taking rivaroxaban in clinical practice. Retrospective study that included patients with nonvalvular atrial fibrillation treated with rivaroxaban for the prevention of stroke between January 2012 and December 2016 in a tertiary hospital in Spain. A total of 142 patients (median age 78 years, 40.1% men, 32.4% creatinine clearance <50 ml/min; 96.5% CHA2DS2-VASc ≥2; 44.3% HAS-BLED ≥3) were included. Only two patients had a thromboembolic event (in both cases ischemic stroke) and three patients had major bleeding (rates of 1.3 and 1.9 events/100 patient years, respectively). Data regarding effectiveness and safety in our cohort were consistent with previous studies, showing that rivaroxaban can be effective and safely used in our setting.

References

Apr 22, 2005·Journal of Thrombosis and Haemostasis : JTH·S SchulmanUNKNOWN Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on T
Aug 13, 2011·The New England Journal of Medicine·Manesh R PatelUNKNOWN ROCKET AF Investigators
Apr 17, 2015·Thrombosis and Haemostasis·John W Eikelboom, Jeffrey I Weitz
Nov 1, 2015·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Ozcan BasaranMurat Biteker
Aug 28, 2016·European Heart Journal·Paulus KirchhofUNKNOWN ESC Scientific Document Group
Mar 21, 2017·Expert Review of Cardiovascular Therapy·Gonzalo Barón-EsquiviasMarcelo Sanmartín Fernandez
Mar 24, 2017·International Journal of General Medicine·Maegan M WhitworthEric J MacLaughlin
Jun 10, 2017·Journal of the American College of Cardiology·Xiaoxi YaoPeter A Noseworthy
Oct 19, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·A John CammEric Peterson

❮ Previous
Next ❯

Citations

Mar 27, 2019·Current Medical Research and Opinion·Cesar Caro MartinezSergio Manzano Fernández
Jul 25, 2019·Current Medical Research and Opinion·Begoña Navarro-AlmenzarSergio Manzano-Fernández
Apr 1, 2021·Journal of Comparative Effectiveness Research·Marcelo Sanmartín FernándezUNKNOWN the EMIR Study Investigators:

❮ Previous
Next ❯

Software Mentioned

XANTUS
AP
SPSS

Related Concepts

Related Feeds

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.