Effectiveness and Tolerability of Natural Herbal Formulations in the Prevention of Radiation-Induced Skin Toxicity in Patients Undergoing Radiotherapy.

The International Journal of Lower Extremity Wounds
Georgios KoukourakisDimitrios Kardamakis

Abstract

The aim of this study is to investigate the preventive role of 3 herbal formulation products on reducing the incidence of radiation-induced dermatitis in patients undergoing radiotherapy for either breast or head and neck cancer. A total of 59 patients participated in the study. The novel herbal products, a combination of beeswax, olive oil, Calendula and Hypericum oils and Aloe gel, were daily and regularly being used by the patients during radiotherapy and 2 weeks after treatment end. Acute skin toxicity was scored weekly during radiotherapy and after treatment for a further 4-week follow-up period. Demographic data were analyzed by descriptive statistics. Statistical analyses of the study objectives were based on an intent-to-treat principle. Most of the patients presented with grade I (RTOG/EORTC) toxicity in the first weeks of radiotherapy, progressed to grade II but reverted to grade I toxicity up until the study end. A total of 94.9% of the patients had Dermatology Life Quality Index up to 1, and 66.1% remained in this scale. The application of the novel natural product combinations proved to be statistically significantly effective in reducing the intensity of radiation dermatitis, positively affecting the quality of li...Continue Reading

References

Mar 1, 1992·Clinical Oncology : a Journal of the Royal College of Radiologists·I R Campbell, M H Illingworth
May 1, 1990·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P J Muller, B C Wilson
Aug 1, 1983·The American Journal of Dermatopathology·J H Dirckx
Sep 1, 1996·International Journal of Radiation Oncology, Biology, Physics·M S WilliamsW D Eggleston
Apr 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P PommierX Montbarbon
May 24, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ethan BaschDeborah Schrag
Sep 10, 2005·Clinical Oncology : a Journal of the Royal College of Radiologists·J RichardsonK Pilkington
Dec 31, 2005·Journal of the American Academy of Dermatology·Sharon R HymesCaroline Fife
Jan 13, 2010·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Sareh SamadiHamid Reza Behnam
Jul 6, 2010·Journal of Medical Imaging and Radiation Oncology·S KumarJ Shafiq
Sep 15, 2010·American Journal of Clinical Oncology·Julie B SchnurGuy H Montgomery
Sep 17, 2010·Journal of Vascular Surgery·Kellie R Brown, Eva Rzucidlo
Apr 26, 2011·Seminars in Oncology Nursing·Maurene McQuestion
Dec 14, 2011·The Journal of Investigative Dermatology·Tamar Nijsten
Jan 6, 2012·The Journal of Investigative Dermatology·Julie L Ryan
Mar 21, 2012·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Martina C MeinkeChristoph M Schempp
Jun 27, 2012·International Journal of Radiation Biology·Nicolas O Fortunel, Michèle T Martin
Dec 19, 2012·European Journal of Oncology Nursing : the Official Journal of European Oncology Nursing Society·Lena SharpMia Bergenmar
Oct 12, 2014·International Journal of Radiation Oncology, Biology, Physics·Jean L WrightJennifer J Hu
May 21, 2015·Revista da Escola de Enfermagem da U S P·Franciane SchneiderStela Adami Vayego
Mar 30, 2016·American Journal of Clinical Dermatology·Manni SinghSadanori Akita
Sep 17, 2016·Asian Pacific Journal of Tropical Medicine·Filippo FratiniAntonio Felicioli
Dec 14, 2016·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Elaine Barros FerreiraPaula Elaine Diniz Dos Reis
Dec 15, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Jaewon LeeSeong Jin Jo

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