PMID: 26323444Sep 2, 2015Paper

Effectiveness of a Chlorhexidine Digluconate 0.12% and Cetylpyridinium Chloride 0.05% Solution in eliminating Candida albicans Colonizing Dentures: A Randomized Clinical in vivo Study

The Journal of Contemporary Dental Practice
Georges AounAntoine Berberi

Abstract

Effective denture hygiene is important for patients suffering from denture stomatitis (DS). This study aimed to evaluate the efficacy of a solution containing 0.12% chlorhexidine (CHX) digluconate and 0.05% cetylpyridinium chloride (CPC) in eliminating Candida albicans colonizing dentures. Forty denture wearers (11 men, 29 women; age range 40 to 80 years) with clinical evidence of DS were randomly divided into two groups, one test and one control. The dentures of the test group were treated by immersion in a solution of 0.12% CHX and 0.05% CPC while those of the control group were immersed in distilled water. Swabs were collected from the fitting surfaces of the upper dentures prior and post cleaner use and examined mycologically. Reduction in the number of colony-forming units (CFU) of Candida albicans after immersion of the dentures in a solution of 0.12% CHX and 0.05% CPC was significantly greater than that of the control group. A solution of 0.12% CHX and 0.05% CPC tested as a product of disinfection of the acrylic dentures showed significant results after immersion of 8 night hours for 4 days.

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Citations

Nov 2, 2018·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Patrícia Almeida CurylofoValéria Oliveira Pagnano
Jan 16, 2020·Journal of Applied Oral Science : Revista FOB·Caroline Vieira MalufDaniel de Moraes Telles
Jun 10, 2020·Antimicrobial Agents and Chemotherapy·Xiaojun MaoFabian Cieplik
Nov 26, 2020·Brazilian Dental Journal·Daniela Nair Borges FelipucciValéria Oliveira Pagnano
Jun 2, 2021·Photodiagnosis and Photodynamic Therapy·Aasem M AlhenakiTariq Abduljabbar

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