Effectiveness of Acellular Dermal Matrix on Autologous Split-Thickness Skin Graft in Treatment of Deep Tissue Defect: Esthetic Subjective and Objective Evaluation

Aesthetic Plastic Surgery
Yoo Jung LeeIl Jae Lee

Abstract

A split-thickness skin graft (STSG) is performed to cover a large full-thickness skin defect. Esthetic and functional deficits can result, and many studies have sought to overcome them. This study compared the effectiveness of the acellular dermal matrix (ADM) graft and STSG concerning esthetic and functional effectiveness of ADM on scar quality. Of the patients who underwent anterolateral thigh free flap from 2011 to 2015, patients who received skin graft only (n = 10) or skin graft with ADM (n = 20) for coverage of the donor site were enrolled. In all cases, autologous STSG was performed with 1:1.5 meshed 0.008-0.010-inch-thick skin. In the skin graft with ADM group, 0.008-0.013-inch-thick meshed ADM (CGderm®; CGBio, Inc., Seungnam, Korea) was co-grafted. Negative-pressure wound therapy (CuraVAC®; CGBio, Inc., Seungnam, Korea) was applied to both groups in continuous mode at -120 mmHg. We investigate early outcomes (skin loss rate, duration of negative-pressure wound therapy, days to removal of stitches, days to achieve complete healing, and complications) and late outcomes in terms of scar quality (vascularity, pigmentation, pliability and height) and graft-related symptoms (itching sensation and pain). Assessments used the ...Continue Reading

References

May 1, 1990·The Journal of Burn Care & Rehabilitation·T SullivanD J Courtemanche
Apr 1, 1984·British Journal of Plastic Surgery·Y G SongY L Song
Mar 1, 1996·The Journal of Burn Care & Rehabilitation·D WainwrightD Herndon
Feb 28, 2001·Burns : Journal of the International Society for Burn Injuries·A M MunsterA Shalom
Dec 18, 2001·Plastic and Reconstructive Surgery·P P van ZuijlenE Middelkoop
Jul 16, 2004·Plastic and Reconstructive Surgery·Lieneke J DraaijersPaul P M van Zuijlen
Oct 7, 2004·Plastic and Reconstructive Surgery·Elias MoisidisAnand K Deva
Jun 27, 2006·Plastic and Reconstructive Surgery·Louis C ArgentaLisa R David
Jan 24, 2007·Burns : Journal of the International Society for Burn Injuries·W HaslikM Frey
Jul 24, 2007·Burns : Journal of the International Society for Burn Injuries·H RysselM Ohlbauer
Sep 11, 2007·Critical Care Medicine·Ludwik K BranskiMarc G Jeschke
Dec 2, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·W HaslikM Frey
Nov 10, 2009·Burns : Journal of the International Society for Burn Injuries·Vincent C van der VeenEsther Middelkoop
May 5, 2010·Plastic and Reconstructive Surgery·Monica C T BloemenEsther Middelkoop
Nov 1, 2012·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Monica C T BloemenEsther Middelkoop
Apr 20, 2013·The Canadian Journal of Plastic Surgery = Journal Canadien De Chirurgie Plastique·Jessica CollinsAchilleas Thoma
Jan 8, 2014·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Shahriar ShahrokhiMarc G Jeschke

❮ Previous
Next ❯

Citations

Mar 9, 2021·Clinics·José da Conceição Carvalho-JúniorLydia Masako Ferreira
Sep 24, 2021·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Alessia PaganelliCristina Magnoni

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.