Effectiveness of antipsychotic drugs in patients with chronic schizophrenia

The New England Journal of Medicine
Jeffrey A LiebermanClinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators

Abstract

The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents has been incompletely addressed, though newer agents are currently used far more commonly. We compared a first-generation antipsychotic, perphenazine, with several newer drugs in a double-blind study. A total of 1493 patients with schizophrenia were recruited at 57 U.S. sites and randomly assigned to receive olanzapine (7.5 to 30 mg per day), perphenazine (8 to 32 mg per day), quetiapine (200 to 800 mg per day), or risperidone (1.5 to 6.0 mg per day) for up to 18 months. Ziprasidone (40 to 160 mg per day) was included after its approval by the Food and Drug Administration. The primary aim was to delineate differences in the overall effectiveness of these five treatments. Overall, 74 percent of patients discontinued the study medication before 18 months (1061 of the 1432 patients who received at least one dose): 64 percent of those assigned to olanzapine, 75 percent of those assigned to perphenazine, 82 percent of those assigned to quetiapine, 74 percent of those assigned to risperidone, and 79 percent of those assigned to ziprasidone. The time to the discontinuation of treatment for any cause was significantly lo...Continue Reading

References

Mar 24, 1998·Archives of General Psychiatry·Gary D TollefsonM E Thieme
Dec 1, 2000·BMJ : British Medical Journal·John R GeddesPaul Bebbington
Jul 4, 2001·Psychopharmacology·Kristian WahlbeckS Leucht
Jan 5, 2002·The New England Journal of Medicine·John CsernanskyRisperidone-USA-79 Study Group
Aug 31, 2002·Harvard Review of Psychiatry·Leslie Citrome, J Volavka
Jun 11, 2003·Archives of General Psychiatry·John M DavisIra D Glick
Aug 12, 2003·Schizophrenia Bulletin·Barry D LebowitzGrayson S Norquist
Sep 25, 2003·JAMA : the Journal of the American Medical Association·Sean R TunisCarolyn M Clancy
Dec 4, 2003·JAMA : the Journal of the American Medical Association·Robert RosenheckDepartment of Veterans Affairs Cooperative Study Group on the Cost-Effectiveness of Olanzapine
Jan 2, 2004·The American Journal of Psychiatry·Dennis S Charney
Jun 23, 2004·Journal of Clinical Psychopharmacology·John M Davis, Nancy Chen
Jan 8, 2005·Psychiatric Services : a Journal of the American Psychiatric Association·Robert Rosenheck

Citations

Sep 29, 2007·Advances in Therapy·Edward KimAndrei Pikalov
Nov 4, 2006·Der Nervenarzt·W Wolfgang Fleischhacker, W Hummer
Sep 13, 2011·Der Nervenarzt·S Bahn, E Schwarz
Oct 18, 2011·Der Nervenarzt·S LeuchtJohn M Davis
Jun 6, 2006·Diabetologia·Richard I G Holt, Robert C Peveler
Aug 23, 2007·Social Psychiatry and Psychiatric Epidemiology·Avi ValevskiRoni Shiloh
Aug 28, 2007·Social Psychiatry and Psychiatric Epidemiology·I SibitzHeinz Katschnig
May 2, 2008·Social Psychiatry and Psychiatric Epidemiology·Hendrik S Temmingh, Piet P Oosthuizen
Jul 29, 2008·Social Psychiatry and Psychiatric Epidemiology·Sylvain GrignonJean Marc Chianetta
Jul 22, 2008·Social Psychiatry and Psychiatric Epidemiology·Kok Yoon Chee
Nov 30, 2010·Social Psychiatry and Psychiatric Epidemiology·Michela NosèC Barbui
Nov 23, 2006·International Urogynecology Journal and Pelvic Floor Dysfunction·H P Dietz
Sep 4, 2009·Naunyn-Schmiedeberg's Archives of Pharmacology·Benoit LabonteGabriella Gobbi
Nov 16, 2011·Naunyn-Schmiedeberg's Archives of Pharmacology·Jelveh LamehDouglas W Bonhaus
Mar 21, 2008·Psychopharmacology·R E NordquistW Spooren
Sep 4, 2008·Psychopharmacology·Cherrie Galletly
Dec 25, 2008·Psychopharmacology·Steven M GrauerSharon Rosenzweig-Lipson
May 23, 2009·Psychopharmacology·Hugh M MarstonMohammed Shahid
Aug 21, 2012·Psychopharmacology·Masaaki OgasaJohn Guarino
Jan 25, 2013·Psychopharmacology·Melanie Dawn GuenetteGary Remington
Jan 30, 2008·European Journal of Clinical Pharmacology·Silvio Garattini, Vittorio Bertele'
Jan 16, 2008·European Journal of Clinical Pharmacology·Christoph Hiemke
Jul 16, 2008·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jurgen Moller
Jun 18, 2009·European Archives of Psychiatry and Clinical Neuroscience·James Bowes Kirkbride, Linda Scoriels
Nov 13, 2009·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jurgen Moller
Oct 20, 2009·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jurgen Moller, Wolfgang Maier
Nov 6, 2009·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jurgen Moller, Karl Broich
Nov 6, 2010·European Archives of Psychiatry and Clinical Neuroscience·Georgios PaslakisMichael Deuschle
Mar 25, 2011·European Archives of Psychiatry and Clinical Neuroscience·Detlef DegnerUdo Reulbach
Nov 23, 2011·European Archives of Psychiatry and Clinical Neuroscience·Hans-Jurgen Moller
Feb 6, 2013·European Archives of Psychiatry and Clinical Neuroscience·Alkomiet HasanSchahram Akbarian
Jun 24, 2006·Wiener klinische Wochenschrift·J EnglC F Ebenbichler
Feb 10, 2009·European Child & Adolescent Psychiatry·Celso ArangoDolores Moreno
Sep 21, 2007·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Reinhard SchnabelFlorian Eichmann
Jul 28, 2011·Wiener medizinische Wochenschrift·Claudia RessChristoph F Ebenbichler
May 12, 2006·Administration and Policy in Mental Health·Daniel J Luchins
Aug 16, 2006·Administration and Policy in Mental Health·Timothy P Tunner, Mark S Salzer
Jun 16, 2006·Administration and Policy in Mental Health·Richard C HermannDebra Lerner
Jun 15, 2006·Administration and Policy in Mental Health·Mark S Salzer, Arthur C Evans
Jul 27, 2007·Administration and Policy in Mental Health·Nancy H CovellSusan M Essock
Apr 12, 2011·Breast Cancer Research and Treatment·Laurent AzoulaySamy Suissa
Jun 15, 2006·Cellular and Molecular Neurobiology·Joseph T Coyle
Aug 4, 2009·Community Mental Health Journal·Larry DavidsonRaquel Andres-Hyman
Nov 30, 2010·Community Mental Health Journal·Greg GreenbergCATIE investigators
Feb 23, 2011·Community Mental Health Journal·Marina EconomouMichael Madianos
Feb 4, 2012·Community Mental Health Journal·Robert M SavageKanini Z Rodney
Mar 27, 2012·Community Mental Health Journal·Christina MangurianMichael J Devlin
Aug 24, 2006·The Psychiatric Quarterly·Richard M BlochChristina Rausch
Aug 24, 2006·The Psychiatric Quarterly·H Steven Moffic
Aug 24, 2006·The Psychiatric Quarterly·Alan D Schmetzer, John J Wernert
Jan 26, 2008·The Psychiatric Quarterly·Juliana I Ekong
Sep 22, 2009·The Psychiatric Quarterly·Somaia MohamedMichael Sernyak
Jan 25, 2012·The Psychiatric Quarterly·Pascale ChrisphonteRobert Rosenheck
Nov 24, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Yu-Tao XiangGabor S Ungvari
Jun 23, 2011·Reviews in Endocrine & Metabolic Disorders·Stephanie Sisley, Darleen A Sandoval
Nov 22, 2007·The Journal of Behavioral Health Services & Research·Justin R Springer, Gordon L Paul
Jul 26, 2012·Current Atherosclerosis Reports·Ronen Durst, Eran Leitersdorf
Jun 1, 2006·Current Psychiatry Reports·Meera Narasimhan, Prahash Masand
Aug 2, 2006·Current Psychiatry Reports·Matcheri S KeshavanDaniela Wittmann
Sep 21, 2007·Current Psychiatry Reports·Rajiv Tandon
Sep 21, 2007·Current Psychiatry Reports·Charles U Nnadi, Anil K Malhotra
Sep 21, 2007·Current Psychiatry Reports·Matcheri S Keshavan, Ali Amirsadri
Sep 21, 2007·Current Psychiatry Reports·Adriana FosterPeter F Buckley
Jan 29, 2008·Current Psychiatry Reports·Michael E Thase
Jan 29, 2008·Current Psychiatry Reports·Andrea Fagiolini, K N Roy Chengappa
Feb 14, 2008·Current Psychiatry Reports·K L BigosR R Bies
Jul 17, 2008·Current Psychiatry Reports·William M Glazer, Mathew J Byerly
Feb 4, 2009·Current Psychiatry Reports·John O BrooksOlya Krasnykh
Jul 29, 2009·Current Psychiatry Reports·Trina Webb, Rajiv Tandon
Feb 14, 2013·Current Psychiatry Reports·Ursula WernekeThomas A B Sanders
Mar 12, 2009·Journal of Molecular Neuroscience : MN·Avril PereiraSuresh Sundram
Aug 12, 2009·Advances in Therapy·Leslie Citrome
Nov 6, 2009·Advances in Therapy·Coleman GrossJoseph K Belanoff
Jan 5, 2013·Clinical Drug Investigation·F CañasMiquel Roca
Nov 13, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ofer AgidGary Remington
Dec 12, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Stephen Z Levine, S Leucht
Dec 14, 2012·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Gagan Fervaha, Gary Remington
May 28, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ofer AgidGary Remington
Apr 9, 2008·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Octavian R Adam, Joseph Jankovic
Dec 27, 2008·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Henry SilverMoussa Youdim
Feb 24, 2006·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Shitij KapurMing Li
May 21, 2013·Psychiatry Research·Paolo Stratta, Alessandro Rossi
Jun 4, 2013·Psychiatry Research·Jack Tsai, Robert Rosenheck
Dec 9, 2008·Lancet·P Tyrer, Tim Kendall
Apr 2, 2009·Psychological Medicine·Stefan LeuchtJohn M Davis
Aug 7, 2009·Psychological Medicine·Ilaria TarriconeDomenico Berardi
Sep 11, 2009·Psychological Medicine·Shôn W Lewis
Oct 12, 2010·Psychological Medicine·M CaseBruce J Kinon
Apr 5, 2013·Psychological Medicine·Amber L BahorikShaun M Eack
Jan 8, 2009·International Journal of Technology Assessment in Health Care·Elizabeth T KinterJohn F P Bridges
Oct 10, 2013·International Psychogeriatrics·A R AttiMarco Menchetti
Oct 24, 2012·Epidemiology and Psychiatric Sciences·M Purgato, C Barbui
Feb 8, 2013·Epidemiology and Psychiatric Sciences·F Cheng, Peter B Jones
May 30, 2013·Epidemiology and Psychiatric Sciences·V C Leeson, P Tyrer
Nov 12, 2010·Nature·Alison Abbott
Jan 22, 2009·European Journal of Human Genetics : EJHG·Anna C NeedDavid B Goldstein
Jan 13, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·H G ShertzerM B Genter
Nov 3, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Gail L DaumitLawrence J Appel
Sep 2, 2009·Molecular Psychiatry·Joseph L McClayEdwin J C G van den Oord
Mar 3, 2010·Molecular Psychiatry·Daniel E AdkinsEdwin J C G van den Oord
Nov 16, 2011·Molecular Psychiatry·Anil K MalhotraTodd Lencz
Apr 27, 2011·Molecular Psychiatry·K L BigosDaniel R Weinberger
Oct 30, 2008·Nature Clinical Practice. Endocrinology & Metabolism·Samuel Dagogo-Jack
Aug 26, 2006·Nature Clinical Practice. Neurology·Kelvin L Chou, Joseph H Friedman
Sep 11, 2007·Nature Medicine·Daniel R Weinberger
Sep 9, 2006·Nature Medicine·David A Lewis, Guillermo Gonzalez-Burgos
Aug 7, 2012·Nature Neuroscience·Mitsumasa KuritaJavier González-Maeso
Aug 30, 2012·Nature Neuroscience·Steven E Hyman
Oct 3, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Philip S WangWayne Goodman
Oct 10, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rima Kaddurah-Daouk, K Ranga Rama Krishnan
Mar 7, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Nicholas M WallingfordMichael A Cowley
Nov 6, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bruce J KinonJohn M Kane
Mar 27, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rakesh KarmacharyaEdgar A Buttner
Aug 26, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·John MarchIra D Glick
Nov 26, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Joseph L McClayEdwin J C G van den Oord
Nov 5, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Prem N YadavBryan L Roth
Jun 18, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Henry A NasrallahDavid Hough
Oct 1, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bita Moghaddam, Daniel C Javitt
Apr 22, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Camilo de la Fuente-SandovalAriel Graff-Guerrero
Aug 9, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Caitlin E McOmishJay A Gingrich
Apr 25, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Yijuan Du, Anthony A Grace
Dec 10, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Steven E Hyman
Oct 5, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Robert E McCullumsmithJames H Meador-Woodruff
Sep 27, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·David M DietzEric J Nestler
Mar 7, 2006·Nature Reviews. Drug Discovery·T Scott StroupJeffrey A Lieberman
May 17, 2008·Nature Reviews. Drug Discovery·Eric M Snyder, Melanie R Murphy
Feb 14, 2009·Nature Reviews. Drug Discovery·Gerhard GründerArvid Carlsson
May 1, 2009·Nature Reviews. Drug Discovery·Darleen A SandovalRandy J Seeley
Oct 31, 2009·Nature Reviews. Drug Discovery·Herbert Y MeltzerPeter Kirkpatrick
Jun 6, 2009·Nature Reviews. Neurology·Russell L Margolis
Dec 16, 2005·Molecular Psychiatry·Thomas R Insel, Edward Scolnick
Mar 17, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Igor ElmanScott E Lukas
May 20, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Murray A RaskindDennis D Rasmussen
Jun 2, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ming LiShitij Kapur
Sep 19, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Tamas Treuer, Jamie Karagianis
Nov 17, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bernard J Carroll, Robert T Rubin
Oct 13, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Karen L HouseknechtHans Rollema
Apr 20, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·David C MamoD P McDonnell
Jul 20, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Peter J WeidenHarold E Lebovitz
Jul 20, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Dilip V JesteKristine Yaffe
Jul 5, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·John M DavisIra D Glick
Aug 10, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Hui-Dong Wang, Ariel Y Deutch
Aug 31, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·David A BakerIlangovan Raju
Aug 23, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Julia SacherSiegfried Kasper
Nov 30, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·William Carpenter, James I Koenig
Oct 11, 2012·Translational Psychiatry·D K Hall-FlavinD A Mrazek
Feb 25, 2009·The Pharmacogenomics Journal·Cc ZaiJames L Kennedy
Dec 24, 2009·The Pharmacogenomics Journal·Chiara PavanBarbara Zavan
Aug 18, 2010·The Pharmacogenomics Journal·Daniel J MüllerJames L Kennedy
Oct 6, 2010·The Pharmacogenomics Journal·Karolina AbergEdwin J C G van den Oord
Nov 17, 2010·The Pharmacogenomics Journal·James J CrowleyPatrick F Sullivan
Aug 3, 2011·The Pharmacogenomics Journal·L GreenbaumBernard Lerer
Jan 4, 2012·The Pharmacogenomics Journal·B AlmogueraSpanish Consortium of Pharmacogenetics Research in Schizophrenia
Jan 20, 2006·The New England Journal of Medicine·Michael Dettling, Ion-George Anghelescu
Sep 21, 2005·The New England Journal of Medicine·Robert Freedman
Feb 3, 2006·The New England Journal of Medicine·John M Davis
Jan 16, 2009·The New England Journal of Medicine·Sebastian Schneeweiss, Jerry Avorn
Mar 23, 2013·The New England Journal of Medicine·Gail L DaumitLawrence J Appel
Jul 6, 2012·The New England Journal of Medicine·Allan H Ropper
Nov 29, 2012·Proceedings of the National Academy of Sciences of the United States of America·Nikhil M UrsMarc G Caron
Apr 28, 2007·The Australian and New Zealand Journal of Psychiatry·Andrea Poyastro PinheiroPatrick F Sullivan
Nov 14, 2007·The Australian and New Zealand Journal of Psychiatry·Marie-Josée PoulinAngelo Tremblay
May 14, 2008·The Australian and New Zealand Journal of Psychiatry·Sanil Rege
Dec 19, 2011·Journal of Sex & Marital Therapy·Mark E BushongMatthew J Byerly
Aug 6, 2010·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Stanley SacksCharles M Cleland
Mar 24, 2010·Journal of Biopharmaceutical Statistics·Jung-Ying TzengPatrick F Sullivan
Jun 2, 2012·Journal of Biopharmaceutical Statistics·Jordan J ElmWenle Zhao
Apr 11, 2006·Harvard Review of Psychiatry·Edward ScolnickPamela Sklar
Jul 28, 2009·Cognitive Neuropsychiatry·Hao-Yang TanDaniel R Weinberger
Jan 1, 2008·Journal of Mental Health Research in Intellectual Disabilities·Lauren CharlotWilliam J McIlvane
Oct 13, 2006·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·David Shannahoff-Khalsa
Sep 2, 2008·Journal of Child and Adolescent Psychopharmacology·Sanjiv KumraJohn M Kane
Sep 2, 2008·Journal of Child and Adolescent Psychopharmacology·Jonathan B JensenS Charles Schulz
Sep 2, 2008·Journal of Child and Adolescent Psychopharmacology·Josefina Castro-FornielesCelso Arango
Oct 22, 2008·Journal of Child and Adolescent Psychopharmacology·Melissa P DelBelloJeffrey J Miceli
Dec 15, 2011·Journal of Child and Adolescent Psychopharmacology·Lawrence Maayan, Christoph U Correll
Apr 20, 2012·Bioinformatics·Phil H LeeShaun M Purcell
Mar 1, 2012·Biometrika·Zhiguo Li, Susan A Murphy
Aug 5, 2006·Schizophrenia Bulletin·Martijn J KikkertRichard J Gray
Apr 7, 2007·Schizophrenia Bulletin·William Carpenter, Gunvant K Thaker
May 2, 2007·Schizophrenia Bulletin·Mark OlfsonH Ascher-Svanum
Jun 15, 2007·Schizophrenia Bulletin·Carol A Tamminga, John M Davis
Jul 10, 2007·Schizophrenia Bulletin·John A Gray, Bryan L Roth
Aug 4, 2007·Schizophrenia Bulletin·Ellen L StoverStephen R Marder
Jul 20, 2007·Schizophrenia Bulletin·Robert RosenheckMichael Sernyak
Nov 7, 2007·Schizophrenia Bulletin·Larry DavidsonRaquel Andres-Hyman
Jan 18, 2008·Schizophrenia Bulletin·John M Kane, S Leucht
Jan 11, 2008·Schizophrenia Bulletin·Robert P McMahonWilliam Carpenter
Feb 5, 2008·Schizophrenia Bulletin·T Scott Stroup, John R Geddes
Feb 1, 2008·Schizophrenia Bulletin·S LeuchtJohn M Kane
Mar 13, 2008·Schizophrenia Bulletin·John M Davis, S Leucht
May 13, 2008·Schizophrenia Bulletin·Andrew C Leon
Jun 20, 2008·Schizophrenia Bulletin·Massimo Moscarelli
Jul 29, 2008·Schizophrenia Bulletin·C LeuchtS Leucht
Jul 23, 2008·Schizophrenia Bulletin·George Foussias, Gary Remington
Sep 13, 2008·Schizophrenia Bulletin·Salvatore Gentile
Aug 30, 2008·Schizophrenia Bulletin·Maria J Arranz, Shitij Kapur
Nov 11, 2008·Schizophrenia Bulletin·Alexander S YoungKirk McNagny
Jun 13, 2009·Schizophrenia Bulletin·Kerry RossPhilippa A Garety
Jun 16, 2009·Schizophrenia Bulletin·Gholson J LyonDavid Sulzer
Mar 31, 2009·Schizophrenia Bulletin·Angus W MacDonald, S Charles Schulz
Jun 3, 2009·Schizophrenia Bulletin·I SibitzM Amering
Dec 4, 2009·Schizophrenia Bulletin·Robert W BuchananSchizophrenia Patient Outcomes Research Team (PORT)
Dec 4, 2009·Schizophrenia Bulletin·Julie KreyenbuhlSchizophrenia Patient Outcomes Research Team (PORT)
May 13, 2011·Schizophrenia Bulletin·J Volavka, Leslie Citrome
Jan 28, 2012·Schizophrenia Bulletin·Chian-Jue KuoChiao-Chicy Chen
Feb 9, 2012·Schizophrenia Bulletin·Edward Chia-Cheng LaiChia-Yin Lin
Nov 1, 2012·Schizophrenia Bulletin·Bernadette A CullenGail L Daumit
Jul 31, 2008·Journal of Psychiatric Practice·Caroline Bonham, Christopher Abbott
Oct 3, 2006·International Clinical Psychopharmacology·M RettenbacherW Wolfgang Fleischhacker
Feb 25, 2011·Academic Medicine : Journal of the Association of American Medical Colleges·Robert R Althoff, G Scott Waterman
Jan 16, 2007·Behavioural Pharmacology·Andrew J GoudieHarry R Sumnall
Aug 24, 2010·Behavioural Pharmacology·Alexandre P MullerLuis V Portela
Aug 14, 2008·Pharmacogenetics and Genomics·Bradley T WebbEdwin J C G van den Oord
Apr 3, 2009·Pharmacogenetics and Genomics·Chadi A CalargeJanet A Schlechte
Jul 14, 2011·Pharmacogenetics and Genomics·Kathryn Kelly Erickson-RidoutPhilip Lazarus
Sep 25, 2008·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Iris GrossmanDavid B Goldstein
Dec 27, 2011·Journal of Clinical Psychopharmacology·Jennifer M PolinskiSebastian Schneeweiss
Aug 18, 2009·The Journal of Nervous and Mental Disease·Stephanie Aldebot, Amy G Weisman de Mamani
May 31, 2007·Southern Medical Journal·James N Kimball
Oct 2, 2007·Southern Medical Journal·Jonathan M Meyer
Oct 2, 2007·Southern Medical Journal·Leslie Citrome
Dec 4, 2008·Clinical Neuropharmacology·Thomas J RaedlerKlaus Wiedemann
Nov 10, 2010·Clinical Neuropharmacology·Ganesan VenkatasubramanianBangalore N Gangadhar
Oct 9, 2007·Current Opinion in Psychiatry·Jessica Broadway, Jacobo Mintzer
Mar 12, 2008·Current Opinion in Psychiatry·Lakshmi P VorugantiA George Awad
Mar 12, 2008·Current Opinion in Psychiatry·Christoph U Correll, Eva M Schenk
Oct 15, 2008·Current Opinion in Psychiatry·Chay-Hoon TanKang Sim
Apr 21, 2009·Current Opinion in Psychiatry·Rajeev Kumar, Perminder S Sachdev
Jan 12, 2010·Current Opinion in Psychiatry·Daniel M BlumbergerZafiris J Daskalakis
Aug 5, 2010·Current Opinion in Psychiatry·Steffen MoritzTodd S Woodward
Sep 15, 2010·Current Opinion in Psychiatry·Thomas J Raedler
Jan 16, 2013·Current Opinion in Psychiatry·Jacob Ballon, T Scott Stroup
Apr 7, 2007·International Clinical Psychopharmacology·David TaylorRobert Kerwin
Apr 7, 2007·International Clinical Psychopharmacology·J PeuskensSOLIANOL Study Group
May 24, 2007·International Clinical Psychopharmacology·Thomas J RaedlerKlaus Wiedemann
Aug 11, 2007·International Clinical Psychopharmacology·Stephan HeresFrank-Gerald Pajonk
Aug 11, 2007·International Clinical Psychopharmacology·A C AltamuraHerbert Y Meltzer
Oct 6, 2007·International Clinical Psychopharmacology·Leslie CitromeJ Volavka
Apr 15, 2008·International Clinical Psychopharmacology·Víctor PérezTESIS Study Group
Jun 12, 2008·International Clinical Psychopharmacology·Carla M CanusoGeorge M Simpson
Jun 6, 2009·International Clinical Psychopharmacology·Erica J DuncanBoadie W Dunlop
Oct 8, 2009·International Clinical Psychopharmacology·Harith S SwadiCandace M Bobier
Nov 18, 2006·Psychiatry and Clinical Neurosciences·Shinsuke NakanishiToshihiko Takahashi
Feb 22, 2008·Psychiatry and Clinical Neurosciences·Nobutomo YamamotoToshiya Inada
May 14, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A McArdleB J Mehigan
May 30, 2009·Diabetes, Obesity & Metabolism·Richard I G Holt, Robert C Peveler
Aug 9, 2006·International Journal of Clinical Practice·R Kerwin
Nov 1, 2006·International Journal of Clinical Practice·F GianfrancescoK Rajagopalan
Mar 9, 2007·International Journal of Clinical Practice·Leslie Citrome
Jul 14, 2007·International Journal of Clinical Practice·A TschonerC F Ebenbichler
Nov 14, 2007·International Journal of Clinical Practice·M ObradovicM Kos
Nov 7, 2007·International Journal of Clinical Practice·Leslie Citrome
Jun 20, 2008·International Journal of Clinical Practice·J Volavka, Leslie Citrome
Jan 27, 2009·International Journal of Clinical Practice·J Volavka
May 1, 2007·Journal for Healthcare Quality : Official Publication of the National Association for Healthcare Quality·Deborra M Torres
Jan 2, 2010·Science·Francis S Collins
Dec 15, 2010·Science Translational Medicine·Robert E Becker, Nigel H Greig
Oct 12, 2012·Science Translational Medicine·Steven E Hyman
Oct 12, 2012·Science Translational Medicine·Thomas R Insel
Oct 14, 2009·Clinical Microbiology Reviews·Roland W Freudenmann, Peter Lepping
Jun 10, 2006·BMJ : British Medical Journal·Rohan Ganguli, Martin Strassnig
Jul 29, 2006·BMJ : British Medical Journal·David Kingdon
Jul 14, 2007·BMJ : British Medical Journal·Marco M Picchioni, Robin M Murray
Oct 24, 2007·BMJ : British Medical Journal·Chittaranjan Andrade
Aug 15, 2006·Annual Review of Medicine·L Fredrik JarskogJeffrey A Lieberman
Jan 11, 2008·Annual Review of Pharmacology and Toxicology·Rima Kaddurah-DaoukRichard M Weinshilboum
Sep 23, 2009·Circulation·Satish R RajDan M Roden
Apr 3, 2009·The Journal of Clinical Investigation·David A Lewis, Robert A Sweet
Apr 3, 2009·The Journal of Clinical Investigation·Thomas R Insel
Mar 1, 2008·Psychiatric Services : a Journal of the American Psychiatric Association·Laurie A LindamerDilip V Jeste
May 3, 2008·Psychiatric Services : a Journal of the American Psychiatric Association·Marisa Elena Domino, Marvin S Swartz
Jul 1, 2009·Psychiatric Services : a Journal of the American Psychiatric Association·Mark OlfsonRonald C Kessler
Oct 15, 2010·Journal of Psychopharmacology·Chris J BusheJari Haukka
Jan 24, 2013·Therapeutic Advances in Chronic Disease·Erik Johnsen, Rune A Kroken
Oct 6, 2010·BMC Psychiatry·Allen W NyhuisBruce J Kinon
Apr 24, 2007·BMC Psychiatry·Manit SrisurapanontNgamwong Jarusuraisin
Apr 29, 2008·BMC Psychiatry·Erik Johnsen, Hugo A Jørgensen
May 29, 2009·Cost Effectiveness and Resource Allocation : C/E·D E FariesH Ascher-Svanum
May 18, 2013·BMC Medicine·Uzoezi OzomaroCharles B Nemeroff
Jan 26, 2013·Annals of General Psychiatry·David M GardnerRichard Williams
Jun 29, 2006·Clinical Practice and Epidemiology in Mental Health : CP & EMH·M De HertJ Peuskens
Sep 5, 2007·Clinical Practice and Epidemiology in Mental Health : CP & EMH·Eric AcquavivaBruno Falissard
Mar 4, 2008·Implementation Science : IS·Paul R FalzerD Melissa Garman
Aug 21, 2013·Child and Adolescent Psychiatry and Mental Health·Gloria M ReevesMark A Riddle
Nov 24, 2012·Journal of Lipid Research·Alberto Canfrán-DuqueRebeca Busto
Jan 16, 2010·Disease Models & Mechanisms·P Alexander ArguelloMaria Karayiorgou
Nov 5, 2010·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Ai TamajiYukihiro Noda
Aug 1, 2007·Healthcare Policy = Politiques De Santé·Daria O'ReillyPatrick Parfrey
Aug 29, 2006·PLoS Medicine·Rima Kaddurah-Daouk
Jan 28, 2014·PloS One·Alexandre Guimarães de Almeida BarrosMarco Aurélio Romano-Silva
Apr 26, 2014·PloS One·Maarten BakMarjan Drukker
May 6, 2009·Health Affairs·Marcela Horvitz-LennonSharon-Lise T Normand
Jul 23, 2009·Health Affairs·David MeltzerHerbert Y Meltzer
May 7, 2008·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Miriam ShuchmanNoni MacDonald
Apr 28, 2010·Journal of Psychiatry & Neuroscience : JPN·Ridha Joober, Patricia Boksa
Jul 27, 2007·The Journal of the American Academy of Psychoanalysis and Dynamic Psychiatry·Paul J Rosenfield
Jul 3, 2013·Pediatrics in Review·Sabina Abidi
Jan 1, 2008·Core Evidence·Joshua Kantrowitz, Leslie Citrome
Sep 15, 2009·Clinical Interventions in Aging·Dhiren Singh, Daniel W O'Connor
Apr 7, 2010·Drug Design, Development and Therapy·Silvio CacciaAlessandro Nobili
Sep 22, 2010·Drug Design, Development and Therapy·Maria Rosaria A MuscatelloRocco Zoccali
Dec 14, 2012·Drug, Healthcare and Patient Safety·Arão Nogueira de AraújoM F Juruena
Jan 1, 2010·Drug, Healthcare and Patient Safety·M F JuruenaIrismar Reis de Oliveira
Jun 16, 2012·Neuropsychiatric Disease and Treatment·Nilufar Mossaheb, Rainer M Kaufmann
Jun 21, 2013·Neuropsychiatric Disease and Treatment·Calvert G Warren, Steven L Dubovsky
May 10, 2012·Neuropsychiatric Disease and Treatment·Silvio CacciaAlessandro Nobili
Aug 9, 2011·Neuropsychiatric Disease and Treatment·Mario R LouzãJosé Carlos Appolinário
Aug 30, 2008·Neuropsychiatric Disease and Treatment·A C Altamura, Jose M Goikolea
Feb 3, 2009·Neuropsychiatric Disease and Treatment·Michael K Rainer
Jun 15, 2013·Neuropsychiatric Disease and Treatment·Tomomi TenjinNoboru Yamaguchi
Jan 29, 2013·Neuropsychiatric Disease and Treatment·Pedro Caldana GordonMario R Louzã
Oct 24, 2009·Neuropsychiatric Disease and Treatment·Xinhua S RenLewis E Kazis
Dec 1, 2006·Neuropsychiatric Disease and Treatment·Leslie Citrome
Dec 1, 2006·Neuropsychiatric Disease and Treatment·Philip E LeePaula Rochon
Apr 1, 2007·Neuropsychiatric Disease and Treatment·Michael RiedelHans-Jürgen Möller
Aug 11, 2012·Patient Preference and Adherence·Louis S MatzaDieter Naber
Feb 22, 2012·Patient Preference and Adherence·W MontgomeryGavan Harrison
Jan 1, 2008·Patient Preference and Adherence·Michael Birnbaum, Zafar Sharif
Aug 10, 2010·Patient Preference and Adherence·Douglas L NoordsyWalter T Linde-Zwirble
Jul 15, 2011·Therapeutics and Clinical Risk Management·L SamalinPierre-Michel Llorca
Dec 28, 2006·CNS Drugs·Tracy Swainston HarrisonSusan J Keam
Feb 8, 2007·CNS Drugs·Peter F BuckleyWilliam C Wirshing
May 20, 2008·CNS Drugs·Trino BaptistaSerge Beaulieu
Jul 5, 2008·Clinical Drug Investigation·Luca PaniKöksal Alptekin
Sep 11, 2009·CNS Drugs·Kayvon SalimiJeffrey A Lieberman
Dec 25, 2009·CNS Drugs·Gary RemingtonOfer Agid
Sep 2, 2010·Applied Health Economics and Health Policy·Marja HensenBen van Hout
Aug 5, 2010·PharmacoEconomics·Silvio Garattini
Jun 10, 2011·Clinical Pharmacokinetics·Erin SchwengerMary H H Ensom
Dec 3, 2011·CNS Drugs·James L RoerigJames E Mitchell
Sep 13, 2012·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Hoda MoteshafiEmmanuel Stip
Jan 7, 2010·The Australian and New Zealand Journal of Psychiatry·Subhrojyoti BhowmickMalati Ghosh
Feb 26, 2010·The Australian and New Zealand Journal of Psychiatry·Stanley V CattsRussell W Evans
Sep 8, 2010·The Journal of Clinical Psychiatry·Stanley N CaroffCATIE Investigators
Oct 7, 2010·The Journal of Clinical Psychiatry·John M Kane, Christoph U Correll
Apr 1, 2011·The Journal of Clinical Psychiatry·Andrew C Leon
Feb 5, 2009·The Journal of Clinical Psychiatry·Daniel M HartungBentson H McFarland
Dec 4, 2009·Primary Care Companion to the Journal of Clinical Psychiatry·J Sloan Manning, Susan L McElroy
Oct 30, 2012·The Primary Care Companion to CNS Disorders·Joel F FarleyMatthew L Maciejewski
Jan 1, 2011·The Primary Care Companion to CNS Disorders·Mina G NashedValerie H Taylor
Jun 13, 2012·The Primary Care Companion to CNS Disorders·Shibu P ThomasSwaran P Singh
Oct 30, 2012·The Primary Care Companion to CNS Disorders·John J BrilesVaibhav A Diwadkar
Mar 4, 2008·Primary Care Companion to the Journal of Clinical Psychiatry·Gabriela BalfRoss A Baker
Oct 1, 2007·Indian Journal of Psychiatry·R K SolankiMukesh K Swami
Jan 1, 2008·Indian Journal of Psychiatry·Roy Abraham Kallivayalil
Oct 14, 2009·Indian Journal of Psychiatry·Rupak Dasgupta, Charu Dasgupta
Jan 6, 2010·Indian Journal of Psychiatry·R K SolankiDeepti Munshi
Apr 5, 2014·Indian Journal of Psychological Medicine·Nisha WarikooSandeep Grover
Aug 21, 2013·Journal of Pharmacology & Pharmacotherapeutics·Rakesh K ChaddaMamta Sood
Aug 25, 2015·Current Treatment Options in Psychiatry·Daniel C Javitt
Sep 12, 2015·The Lancet. Psychiatry·Dorien H Nieman
Sep 10, 2011·Neural Plasticity·Guillermo Gonzalez-BurgosDavid A Lewis
Nov 19, 2013·Journal of Comparative Effectiveness Research·Brian GodmanSteven Simoens
Aug 13, 2013·Pharmacogenomics·Mao Mao Söderberg, Marja-Liisa Dahl
Aug 28, 2012·Pharmacogenomics·Qian LiuMark D Brennan
Dec 12, 2013·Biomarkers in Medicine·Colin T Dourish, Gerard R Dawson
Jan 24, 2014·BMC Psychiatry·Jean LachaineMaud Beillat
Feb 4, 2014·Psychopharmacology·Jan BrosdaHeinz H Pertz
Feb 20, 2013·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Simon FreyTom Stargardt
Feb 11, 2014·Journal of Psychiatric Research·Gagan FervahaGary Remington
Nov 14, 2013·Schizophrenia Research and Treatment·Vaios PeritogiannisVenetsanos Mavreas
Sep 24, 2013·The Psychiatric Quarterly·J Volavka
Jan 3, 2014·Clinical Epigenetics·Melkaye G MelkaShiva M Singh
Sep 20, 2006·Pharmacogenomics·Daniel J Müller, James L Kennedy