Effectiveness of brief alcohol interventions for general practice patients with problematic drinking behavior and comorbid anxiety or depressive disorders

Drug and Alcohol Dependence
Janina M GrothuesHans-Jürgen Rumpf

Abstract

Brief interventions (BIs) are effective methods to reduce problematic drinking. It is not known, if the effectiveness of BI differs between patients with or without comorbid depression or anxiety disorders. In a randomized controlled BI study with two intervention groups and one control condition, data were collected from 408 general practice (GP) patients with alcohol use disorders, at-risk drinking or binge drinking. 88 participants were diagnosed with comorbid anxiety and/or depressive disorders. The effectiveness of BI was assessed at a 12-month follow-up in relation to the presence and absence of comorbidity. Reduction of drinking in six ordered categories (g/alcohol) between baseline and follow-up served as the outcome variable. BI were significantly related to reduction of drinking in the non-comorbid (-2.64 g/alcohol vs. -8.61 g/alcohol; p=.03) but not in the comorbid subsample (-22.06 g/alcohol vs. -22.09 g/alcohol; p=.76). Compared to non-comorbid participants, a significantly higher reduction of drinking was found for comorbid individuals (-6.55 g/alcohol vs. -22.08 g/alcohol; p=.01). An ordinal regression analysis revealed comorbidity to be a positive predictor for reduction of drinking (estimator=.594; CI=.175-1.01...Continue Reading

References

Sep 28, 1991·BMJ : British Medical Journal·P Anderson
Nov 21, 1990·JAMA : the Journal of the American Medical Association·D A RegierF K Goodwin
Mar 1, 1993·Addiction·T H BienJ S Tonigan
May 1, 1997·Alcoholism, Clinical and Experimental Research·P R StasiewiczG J Connors
Aug 1, 1997·Alcoholism, Clinical and Experimental Research·H J RumpfU John
Mar 24, 1998·Archives of General Psychiatry·S F GreenfieldJ Michael
May 11, 2002·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Hans-Jürgen RumpfUlrich John
Sep 7, 2002·Archives of General Psychiatry·Deborah S Hasin, Bridget F Grant
Jul 6, 2005·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Janina GrothuesHans-Jürgen Rumpf

❮ Previous
Next ❯

Citations

Mar 17, 2010·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·H Küfner
Sep 25, 2012·Journal of Substance Abuse Treatment·Derek D SatreConstance Weisner
Dec 24, 2009·Alcoholism, Clinical and Experimental Research·Sarah W Feldstein EwingKent E Hutchison
Aug 19, 2011·Substance Abuse Treatment, Prevention, and Policy·Nelson FeldmanDaniele Zullino
Jan 3, 2018·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Sadie BonifaceZarnie Khadjesari
Feb 25, 2018·The Cochrane Database of Systematic Reviews·Eileen Fs KanerBernard Burnand
Dec 13, 2016·Australian Journal of Primary Health·Breanne HobdenMariko Carey
Jul 28, 2013·Revista brasileira de enfermagem·Maria Odete PereiraLuciana de Almeida Colvero
Nov 27, 2019·The Cochrane Database of Systematic Reviews·Leanne HidesAmanda Baker

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.