PMID: 9424327Jun 1, 1997Paper

Effectiveness of combined therapy in patients with clear cell carcinoma of the kidney

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
M Muc-WierzgońK Madej

Abstract

The paper presents preliminary results of a combined therapy consisted of INF-alpha, TNF-alpha and Vinblastine administrated to 12 patients with advanced clear cell carcinoma of kidney. All patients accrued into this protocol underwent unsuccessful conventional oncological treatment. In 2 subjects the treatment was interrupted because of acute adverse events during the first course of the combined therapy. In the remaining group: 3 patients showed long term partial remission (PR) (follow up time up to 9.5 months) and 4 patients responded with minor/stable disease. The disease progression was observed in 2 patients.

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