Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review

JBI Database of Systematic Reviews and Implementation Reports
Jeffrey Hoffman, Casi Hamner

Abstract

Postanesthetic shivering remains a significant source of distress following general anesthesia. Despite numerous studies investigating pharmacologic prophylaxis for postanesthetic shivering, no gold standard medication has been identified. Prophylactic dexmedetomidine administration has been examined as a possible preventative treatment modality for postanesthetic shivering; however its effectiveness has not been established. The objective of this review was to evaluate the effectiveness of intravenous prophylactic dexmedetomidine for reduction of postanesthetic shivering during the first two hours after general anesthesia. The participants included in this study were adults between 18 and 68 years of age receiving general anesthesia for any surgical procedure. Only participants with American Society of Anesthesiologist physical status I or II were included. Types of intervention(s): This review evaluated the effectiveness of intravenous dexmedetomidine in preventing postanesthetic shivering. Studies that compared preoperative or intraoperative administration of dexmedetomidine to placebo were included. Types of studies: The studies included in this review were all randomized controlled trials. Types of outcomes: This review as...Continue Reading

References

Jan 31, 2002·Anesthesiology·Jan De Witte, Daniel I Sessler
Apr 2, 2005·Journal of Applied Physiology·Shizue MasukiJohn H Eisenach
Dec 22, 2005·Proceedings·R GertlerE N Silvius
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Aug 1, 2007·Revista brasileira de anestesiologia·Viviane Ferreira AlbergariaFrederico Augusto Soares de Lima
Feb 22, 2012·Journal of Anaesthesiology, Clinical Pharmacology·Sukhminder Jit Singh BajwaSs Parmar
May 7, 2013·Korean journal of anesthesiology·Cheol LeeJi-Na Kim
Aug 29, 2013·International Journal of Medical Sciences·Yong-Shin KimHye-Rim Kang
Apr 9, 2015·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Zhen-Xiu LiuZui Zou
Oct 9, 2015·JBI Database of Systematic Reviews and Implementation Reports·Jeffrey Hoffman, Casi Hamner

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Citations

Sep 29, 2019·Acta Paediatrica·Paula HäkkänenTiina Laatikainen
Mar 2, 2021·Neurosurgery·Chanhung Z Lee, Clara C M Poon

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