Effectiveness of different adjuvants in stimulating Dichelobacter nodosus antibody in sheep vaccinated against ovine footrot

Acta Veterinaria Hungarica
P Martín-PalominoS Vadillo

Abstract

This research consists of an evaluation of the effectiveness of different substances administered as adjuvants in the stimulation of humoral immune response induced by the vaccine composed of strains A1, A2 and C of Dichelobacter nodosus. To do this, a total of 120 Merino sheep were vaccinated and revaccinated. These sheep were selected from a farm located in the region of Extremadura (Spain), and they were divided into 12 groups of 10 animals each. An additional group with 10 sheep was used as control. The immune response (titre of antibodies) was determined by agglutination tests and ELISA. The most pronounced immune response was obtained by the use of Freund's incomplete adjuvant and aluminium hydroxide as adjuvants.

References

Sep 1, 1979·The Veterinary Record·D M Barber
Oct 13, 1979·The Veterinary Record·A de L Banting
Apr 1, 1986·Australian Veterinary Journal·D J StewartI J O'Donnell
Dec 1, 1986·Australian Veterinary Journal·R G Lambell
Apr 1, 1971·Journal of Comparative Pathology·J R Egerton, D S Roberts
Dec 1, 1996·FEMS Microbiology Letters·S J BillingtonJ I Rood
Jun 14, 2001·Acta Veterinaria Hungarica·S PírizS Vadillo

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Citations

Jul 28, 2009·Veterinary Immunology and Immunopathology·Asunción RamosMaría-Prado Míguez
Feb 7, 2009·Journal of Pineal Research·Sergio RegodónJuan A Rosado
Aug 2, 2005·Vaccine·Sergio RegodónDavid Pozo
Apr 17, 2014·Vaccine·Om DhungyelRichard Whittington

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