Effectiveness of energy conservation management on fatigue and participation in multiple sclerosis: A randomized controlled trial

Multiple Sclerosis : Clinical and Laboratory Research
Lyan Jm BlikmanTREFAMS-ACE Study Group

Abstract

Fatigue is a frequently reported and disabling symptom in multiple sclerosis (MS). To investigate the effectiveness of an individual energy conservation management (ECM) intervention on fatigue and participation in persons with primary MS-related fatigue. A total of 86 severely fatigued and ambulatory adults with a definite diagnosis of MS were randomized in a single-blind, two-parallel-arm randomized clinical trial to the ECM group or the information-only control group in outpatient rehabilitation departments. Blinded assessments were carried out at baseline and at 8, 16, 26 and 52 weeks after randomization. Primary outcomes were fatigue (fatigue subscale of Checklist Individual Strength - CIS20r) and participation (Impact on Participation and Autonomy scale - IPA). Modified intention-to-treat analysis was based on 76 randomized patients (ECM, n = 36; MS nurse, n=40). No significant ECM effects were found for fatigue (overall difference CIS20r between the groups = -0.81; 95% confidence interval (CI), -3.71 to 2.11) or for four out of five IPA domains. An overall unfavourable effect was found in the ECM group for the IPA domain social relations (difference between the groups = 0.19; 95% CI, 0.03 to 0.35). The individual ECM for...Continue Reading

References

Jan 1, 1996·Journal of Clinical Epidemiology·C A van BennekomL M Bouter
Aug 28, 1998·Journal of Psychosomatic Research·H FordM Johnson
Apr 11, 2001·Archives of Physical Medicine and Rehabilitation·V MathiowetzM E Murphy
Nov 8, 2002·Archives of Physical Medicine and Rehabilitation·Mieke CardolRob J de Haan
Jun 6, 2003·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Susan M VanageVirgil Mathiowetz
Aug 27, 2005·Clinical Rehabilitation·Priyanka S MallikLouis Fogg
Oct 1, 2005·Multiple Sclerosis : Clinical and Laboratory Research·Virgil G MathiowetzPing Luo
Oct 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Marieke F M GielissenGijs Bleijenberg
Feb 17, 2007·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Kathleen MatuskaMarcia Finlayson
Jul 12, 2007·Multiple Sclerosis : Clinical and Laboratory Research·D KosE Kerckhofs
Sep 14, 2007·Disability and Rehabilitation·Paula KerstenBarney White
Nov 3, 2007·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Virgil G MathiowetzHua Yun Chen
Jan 23, 2008·Multiple Sclerosis : Clinical and Laboratory Research·C SauterK Vass
Oct 31, 2008·Lancet·Alastair Compston, Alasdair Coles
Jan 27, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Steve VucicMatthew C Kiernan
May 13, 2011·Multiple Sclerosis : Clinical and Laboratory Research·Marcia FinlaysonMatthew Plow
Jul 4, 2012·Clinical Rehabilitation·E Guiomar García JalónAndrea Lowe-Strong
Jan 15, 2013·Scandinavian Journal of Occupational Therapy·Carlijn H van der ZeeMarcel W M Post
Feb 13, 2013·Archives of Physical Medicine and Rehabilitation·Lyan J BlikmanJetty van Meeteren
Jul 30, 2014·Disability and Rehabilitation·Miho AsanoMarcia L Finlayson

❮ Previous
Next ❯

Citations

Aug 31, 2019·Multiple Sclerosis : Clinical and Laboratory Research·Matthew Plow, Marcia Finlayson
Jul 10, 2020·Scandinavian Journal of Occupational Therapy·Éle Quinn, Sinéad M Hynes
Apr 27, 2018·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Anna L KratzSusan L Murphy
Jul 10, 2019·Scandinavian Journal of Occupational Therapy·Eva Månsson LexellTanya Packer
Jul 19, 2019·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Lyan J M BlikmanUNKNOWN TREFAMS-ACE Study Group
Feb 18, 2020·Frontiers in Neurology·Arjan MalekzadehCharlotte E Teunissen
Oct 28, 2019·Journal of the Neurological Sciences·Katie L J CederbergRobert W Motl
Mar 9, 2021·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Esther T Kruitwagen-Van ReenenJohanna Visser-Meily
Feb 23, 2021·Internet Interventions : the Application of Information Technology in Mental and Behavioural Health·Kirsten van KesselSarah Thomas
Apr 21, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Anthony M HarrisonSam Norton
Jul 2, 2021·Disability and Health Journal·Katie L J CederbergRobert W Motl

❮ Previous
Next ❯

Methods Mentioned

BETA
Cognitive Behavioural Therapy

Software Mentioned

TREFAMS
SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.