Effectiveness of enhanced external counterpulsation in patients with left main disease and angina

Clinical Cardiology
W E LawsonIEPR investigators

Abstract

Enhanced external counterpulsation (EECP) is a noninvasive device that uses three pairs of sequentially inflated pneumatic cuffs applied to the lower extremities and synchronized with the heart beat to provide diastolic augmentation, increase coronary blood pressure and flow, venous return and cardiac output, and decrease afterload. This study examines the safety and effectiveness of EECP therapy in patients with significant left main coronary artery disease (LMD). In all, 2,861 patients enrolled in the International EECP Patient Registry (IEPR) were divided into three groups, those without LMD (n = 2,377), those with LMD and prior CABG (n = 431), and those with unbypassed LMD (n = 53). Patients with LMD, with or without prior CABG, were significantly more likely to have triple-vessel disease (98.1 and 88.7%, respectively) than patients without LMD (41.9%). Post-EECP, 74% without LMD, 75% with LMD with prior CABG, and 65% with unbypassed LMD improved their Canadian Cardiovascular Society (CCS) angina by at least one class (p = NS). There were no differences in the mean decrease in weekly angina episodes (7.1 vs. 8.0 vs. 7.6) and in the mean frequency of weekly nitroglycerin use (6.6 vs. 8.1 vs. 8.9). At 6-month follow-up, the C...Continue Reading

References

May 1, 1978·Circulation·M J ConleyR A Rosati
Oct 1, 1992·The American Journal of Cardiology·W E LawsonP F Cohn
Oct 2, 1998·Clinical Cardiology·K SureshP F Cohn
May 12, 2000·Journal of the American College of Cardiology·M SilvestriB Comet
Jun 14, 2001·Clinical Cardiology·G BarsnessUNKNOWN International EECP Patient Registry Investigators
Jan 30, 2002·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Rohit R AroraSusan Keller
May 28, 2003·Journal of the American College of Cardiology·Piero O BonettiAmir Lerman

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Citations

Oct 19, 2006·Progress in Cardiovascular Diseases·Peter F Cohn
Oct 27, 2016·Clinical Physiology and Functional Imaging·Michael MelinEric Rullman
Mar 2, 2006·Clinical Cardiology·William E LawsonUNKNOWN International Enhanced External Counterpulsation Patient Registry Investigators

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