Effectiveness of genomic selection for improving provitamin A carotenoid content and associated traits in cassava.

G3 : Genes - Genomes - Genetics
Williams EsumaRobert S Kawuki

Abstract

Global efforts are underway to develop cassava with enhanced levels of provitamin A carotenoids to sustainably meet increasing demands for food and nutrition where the crop is a major staple. Herein, we tested the effectiveness of genomic selection (GS) for rapid improvement of cassava for total carotenoids content and associated traits. We evaluated 632 clones from Uganda's provitamin A cassava breeding pipeline and 648 West African introductions. At harvest, each clone was assessed for level of total carotenoids, dry matter content, and resistance to cassava brown streak disease (CBSD). All clones were genotyped with diversity array technology and imputed to a set of 23,431 single nucleotide polymorphic markers. We assessed predictive ability of four genomic prediction methods in scenarios of cross-validation, across population prediction, and inclusion of quantitative trait loci markers. Cross-validations produced the highest mean prediction ability for total carotenoids content (0.52) and the lowest for CBSD resistance (0.20), with G-BLUP outperforming other models tested. Across population, predictions showed low ability of Ugandan population to predict the performance of West African clones, with the highest predictive ab...Continue Reading

References

Sep 23, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·John Bongaarts
Oct 14, 2009·Genetics·A P W de RoosM E Goddard
Feb 17, 2010·Briefings in Functional Genomics·Jean-Luc JanninkHiroyoshi Iwata
Feb 19, 2010·Plant Foods for Human Nutrition·Alison GegiosMark J Manary
Jul 2, 2011·Food and Nutrition Bulletin·Howarth E BouisWolfgang H Pfeiffer
Jun 6, 2012·Methods in Molecular Biology·Andrzej KilianGrzegorz Uszynski
Jul 11, 2013·PloS One·Deepak K RayJonathan A Foley
Sep 18, 2013·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Catherine B KandianisTorbert Rocheford
Jun 28, 2014·Trends in Plant Science·Zeratsion Abera Desta, Rodomiro Ortiz
Jul 11, 2014·Genetics·Paulino Pérez, Gustavo de los Campos
Nov 2, 2014·Frontiers in Genetics·Gota Morota, Daniel Gianola
Oct 27, 2016·PloS One·Nanna Hellum NielsenJust Jensen
Nov 1, 2016·Breeding Science·Robert Sezi KawukiYona Baguma
Jan 31, 2017·Methods in Molecular Biology·Julio Isidro-SánchezGracia Montilla-Bascón
Jul 15, 2017·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·E A MasumbaM E Ferguson
Oct 3, 2017·Trends in Plant Science·José CrossaRajeev K Varshney
Nov 23, 2017·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·G de Los Campos, M Á Toro
Jan 3, 2018·The Plant Genome·Marnin D WolfeJean-Luc Jannink
Jan 26, 2018·Scientific Reports·Siraj Ismail KayondoJean-Luc Jannink
Aug 14, 2018·American Journal of Human Genetics·Brian L BrowningSharon R Browning
Oct 31, 2018·G3 : Genes - Genomes - Genetics·Alfred OzimatiJean-Luc Jannink
May 30, 2019·Foods·Toluwalope Emmanuel EyinlaRasaki Ajani Sanusi
Jun 19, 2019·Nature Biotechnology·Lee T HickeyBrande B H Wulff
Oct 6, 2020·The Plant Genome·Inés BerroLucía Gutiérrez
Oct 16, 2019·Plant Communications·Yunbi XuAimin Zhang
Jul 1, 2009·Comprehensive Reviews in Food Science and Food Safety·Julie A MontagnacSherry A Tanumihardjo

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