Effectiveness of intensity-modulated and image-guided radiotherapy to spare the mandible from excessive radiation

Oral Oncology
Nam P NguyenVincent Vinh-Hung

Abstract

We would like to assess the effectiveness of intensity-modulated radiotherapy (IMRT) or image-guided radiotherapy (IGRT) to decrease the risk of osteoradionecrosis in locally advanced head and neck cancer. We conducted a retrospective study of 83 patients with head and neck cancer undergoing concurrent definitive chemoradiation, post-operative radiotherapy or chemoradiation, or radiotherapy alone with IMRT or IGRT. Mean mandibular dose was, respectively, 43.6Gy and 43.8Gy for the IMRT and IGRT technique. At a median follow-up of 28 months (5-55 months), only one patient developed osteoradionecrosis requiring hyperbaric oxygen. Sharp dose falloff associated with IMRT and IGRT decreased excessive radiation of the mandible and may reduce the risks of osteoradionecrosis.

References

Oct 1, 1987·Oral Surgery, Oral Medicine, and Oral Pathology·R E Marx, R P Johnson
Jan 1, 1985·Head & Neck Surgery·D RemmlerK Pfalzgraf
May 25, 2002·Cancer Treatment Reviews·Barbara A Jereczek-Fossa, Roberto Orecchia
Feb 1, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Barbara A Jereczek-FossaRoberto Orecchia
Mar 21, 2006·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Claudio FiorinoRicardo Calandrino
Oct 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Batya R GoldwaserMeredith August
Aug 19, 2008·International Journal of Radiation Oncology, Biology, Physics·Daniel R GomezNancy Y Lee
Mar 31, 2009·International Journal of Radiation Oncology, Biology, Physics·Ik Jae LeeIn Ho Cha
May 26, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Lin WangGui-Qing Liao
Jun 23, 2009·International Journal of Radiation Oncology, Biology, Physics·Avraham EisbruchK Kian Ang
Aug 4, 2009·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Merina AhmedChristopher M Nutting
Mar 2, 2010·Oral Oncology·Nam P NguyenLexie Smith-Raymond
May 12, 2010·Oral Oncology·C MadridK Bouferrache
Jun 8, 2010·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Douglas E PetersonMichael T Brennan
Oct 13, 2010·The Laryngoscope·William M MendenhallJonathan G Li
Dec 21, 2010·International Journal of Radiation Oncology, Biology, Physics·Michael E MontejoYing J Hitchcock
Apr 13, 2011·Head & Neck·Shamit ChopraJohn Jacobs
Apr 16, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Yan MonnierBertrand Jaques

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Citations

Nov 6, 2014·Photomedicine and Laser Surgery·Meire Maman Fracher AbramoffLydia Masako Ferreira
Dec 26, 2015·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Jan-Dirk RaguseCarmen Stromberger
Apr 4, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Francesca De FeliceTeresa Guerrero Urbano
Dec 27, 2015·Head & Neck·Stanley I GutiontovRuben Cabanillas
May 18, 2016·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Alan T MonroeAnuj V Peddada
Jun 19, 2013·The Laryngoscope·Davide FranceschiniGiampaolo Biti
Mar 31, 2015·Oral Oncology·Francesca De FeliceVincenzo Tombolini
Nov 9, 2016·Critical Reviews in Oncology/hematology·Francesca De FeliceVincenzo Tombolini
Jul 10, 2020·Current Oncology Reports·Francesca De FeliceAntonella Polimeni

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