PMID: 8592174Jan 1, 1995Paper

Effectiveness of intraoperative radiation therapy for recurrent supratentorial low grade glioma

Journal of Neuro-oncology
A HaraS Yanagawa

Abstract

Twelve adult patients in the records of 38 patients with histologically verified supratentorial low grade glioma showed recurrence at the Gifu University Hospital between 1980 and 1992. A mean period to recurrence from the initial surgery and postoperative radiation was 38 months. Six of these patients underwent intraoperative radiation therapy. The other six patients received chemotherapy with conventional cytoreductive surgery in three cases and additional external irradiation in three cases. The 2-year survival rate of the former patients was 83.8% and significantly higher than that of the latter ones, 16.7% (p < 0.05). Most cases showing recurrence of supratentorial low grade glioma were occurred locally, and dissemination or remote metastasis of the lesion were rare. The results revealed that the local control is important for recurrent tumors of supratentorial low grade gliomas. The effectiveness of the intraoperative radiation therapy as the second operation for the recurrent supratentorial benign glioma is discussed.

References

Oct 1, 1992·Neurosurgery·B M McCormackJ Ransohoff
Nov 1, 1991·Neurologia Medico-chirurgica·N SakaiS Yanagawa
Apr 1, 1990·International Journal of Radiation Oncology, Biology, Physics·A C Whitton, H J Bloom
Sep 1, 1989·Journal of Neurosurgery·T HoshinoR L Davis
May 1, 1988·Journal of Neurosurgery·P C BurgerP Kleihues
Jan 1, 1987·Journal of Neurosurgery·S A Leibel, G E Sheline
Apr 1, 1988·Neurology·L A CivitelloL Schut

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Citations

Apr 13, 2000·International Journal of Radiation Oncology, Biology, Physics·J DebusM Wannenmacher
Sep 1, 2007·BMC Cancer·Stephanie E CombsDaniela Schulz-Ertner
Aug 3, 2012·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Sergey UsychkinHugo Marsiglia

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