Effectiveness of Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) in the uterine adenomyosis treatment: technical approach and MRI evaluation

La Radiologia medica
Fabiana FerrariCarlo Masciocchi

Abstract

To evaluate the treatment efficacy of uterine adenomyosis using MRgFUS as a mini-invasive therapy. Twenty-three patients affected by symptomatic uterine adenomyosis (11 focal and 7 diffuse forms), diagnosed using MRI, were included in this study. Eighteen out of 23 were submitted to MRgFUS. All junctional zone more than 12 mm in width were considered to be adenomyosis. Study evaluates the pre-treatment target volume measured prior to the treatment on the CE T1-weighted sequence and the MRgFUS-treated volume (MRgFUS-TV), represented by the volume of the lesion ablated, measured directly by means of the MRgFUS. The treated volume on the CE T1-weighted sequence (CE MRI-TV) was measured immediately after treatment. After 1 year, the junctional zone thickness was measured in order to compare pre- and post-treatment values. The therapeutic plan consisted of a high-energy-grid sonication. Symptomatology was assessed through the UFS-QOL. The pre-treatment target volume mean value was of 59.7 cc; the MRgFUS-TV had a mean value of 44.9 cc, and the mean value of CE MRI-TV, measured immediately after treatment, was of 52.8 cc, with an increase of 13.7%. The 86.5% of the lesion was treated. After 1 year from the treatment, 15/18 (83%) patie...Continue Reading

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Citations

Nov 5, 2016·Best Practice & Research. Clinical Obstetrics & Gynaecology·Jason A Abbott
Jul 1, 2017·Current Opinion in Obstetrics & Gynecology·Farah A AlviMagdy P Milad
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Nov 6, 2020·Seminars in Reproductive Medicine·Joseph ChenKimberly A Kho
Jun 19, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Lu LiuBaiying Lei

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