Sep 10, 2019

Effectiveness of Strontium-89 for Neuropathic Pain Caused by Bone Metastases from Breast Cancer: A Case Report

Kaku igaku. The Japanese journal of nuclear medicine
Yusuke IizukaTakashi Mizowaki

Abstract

The patient was a 47-year-old female with stage IV breast cancer and multiple bone metastases. She received various systemic therapies (hormone therapy and chemotherapy) and underwent mastectomy between 2013 and 2018; in the beginning of 2018, she started experiencing bone metastatic pain in the right hip joint and neural pain on the dorsal side of the left thigh. These symptoms worsened gradually, and nonsteroidal anti-inflammatory analgesics or narcotic analgesics were not effective for treating this pain. Strontium-89 (89Sr) treatment was administered in April 2018. The pain was relieved immediately after 89Sr treatment. The patient's quality of life improved markedly. She spent her remaining life without using analgesic drugs, until she died in October 2018 due to exacerbation of the original disease. Although radiotherapy is believed to be less effective for neuropathic pain than for bone metastatic pain, it should be considered as a treatment option in patients with neuropathic pain.

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Mentioned in this Paper

Anti-Inflammatory Agents, Non-Steroidal
Analgesics
Originality
Secondary Malignant Neoplasm of Bone
Administration of Antineoplastic Agent
Hormone Therapy
Strontium-89
Therapeutic Radiology Procedure
Right Hip Joint Structure
Narcotic Analgesics

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