Effectiveness of Thermal Ablation for Aldosterone-Producing Adrenal Adenoma: A Systematic Review and Meta-Analysis of Clinical and Biochemical Parameters

Journal of Vascular and Interventional Radiology : JVIR
Keng-Wei LiangHsin-Hui Huang

Abstract

To assess the effectiveness of thermal ablation for aldosterone-producing adrenal adenoma. A systematic search of the PubMed and CINAHL databases was performed to identify studies of thermal ablation for adrenal adenomas. Random effects meta-analysis models were used to compare pre- and post-treatment values of the following outcomes: systolic blood pressure (SBP), diastolic blood pressure (DBP), use of antihypertensive medications, and biochemical parameters (plasma aldosterone levels, aldosterone-to-renin ratio, and potassium levels). The rate of hypertension (HTN) resolution and improvement were also evaluated. A total of 89 patients from 7 studies were included in the analysis. The mean postablation follow-up duration was 45.8 months. Pooled data analysis revealed a statistically significant decrease in SBP (-29.06 mm Hg; 95% confidence interval [CI], -33.93 to -24.19), DBP (-16.03 mm Hg; 95% CI, -18.33 to -13.73), and the number of antihypertensive medications used (-1.43; 95% CI, -1.97 to -0.89) after ablation. Biochemical parameters had returned to normal ranges after ablation in all studies. The cumulative rate of resolution or improvement in HTN status was 75.3%. On metaregression analysis, there was no statistically s...Continue Reading

References

Nov 1, 1991·The Journal of Clinical Endocrinology and Metabolism·T J McKennaS Cunningham
Jun 1, 1996·Archives of Surgery·O CelenR M Beazley
Aug 1, 1996·Annals of Surgery·C Y LoJ Wong
May 8, 1999·The European Journal of Surgery = Acta Chirurgica·P Sapienza, A Cavallaro
Aug 21, 2001·Annals of Internal Medicine·A M SawkaJ A van Heerden
Jun 28, 2008·Cardiovascular and Interventional Radiology·Hilmar KuehlGerald Antoch
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Oct 29, 2010·Radiology·Mishal Mendiratta-LalaS Nahum Goldberg
Oct 30, 2012·International Surgery·Wei WangHai Huang
May 25, 2013·AJR. American Journal of Roentgenology·Raul N Uppot, Debra A Gervais
Feb 11, 2014·Journal of Vascular and Interventional Radiology : JVIR·Brian T WelchThomas D Atwell
May 23, 2015·Radiology·Takaaki HasegawaYoshiki Sugimura
Aug 2, 2015·Journal of Vascular and Interventional Radiology : JVIR·Denis SzejnfeldSuzan Menasce Goldman
Mar 5, 2016·The Journal of Clinical Endocrinology and Metabolism·John W FunderWilliam F Young
May 6, 2016·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Chao RenJie Yu
Jun 1, 2016·Journal of Vascular and Interventional Radiology : JVIR·Ammar SarwarSalomao Faintuch
Mar 2, 2017·Current Opinion in Endocrinology, Diabetes, and Obesity·Barry A SacksSalomao Faintuch

❮ Previous
Next ❯

Citations

Jan 1, 2020·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Yu-Fei FuYa-Yong Huang
Sep 16, 2020·Journal of Human Hypertension·Maurizio CesariGian Paolo Rossi
Dec 17, 2020·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Christina LobergLars Schimmöller
Dec 3, 2020·Endocrinology and Metabolism·Byung Kwan Park
Jun 4, 2021·Current Cardiology Reports·Heather Wachtel, Douglas L Fraker
Jun 11, 2021·Endocrinology and Metabolism·Byung Kwan ParkUei Pua

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie
S Etker, E A Enger
Postgraduate Medical Journal
J M Calvo-Romero, J L Ramos-Salado
© 2021 Meta ULC. All rights reserved