PMID: 6111878Jan 1, 1981Paper

Effectiveness of treating early-onset malignant schizophrenia with psychotropic drugs and their combinations

Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova
E S Sobolev, S G Zaĭtsev

Abstract

The effectiveness of 1211 treatment courses given to 96 patients with "nuclear" schizophrenia was estimated by statistical methods with consideration of the therapy form (individual psychotropic drugs or their combinations) and the clinical variants of the disease. A number of statistically significant effects produced by these two factors and their interaction was revealed. The direction of the effects points to a relative advantage of the combined pharmacotherapy that envisages simultaneous use of drugs with different spectrum of action. In different variants of the disease, the efficacy of each of the 10 forms of the therapy was different: rather peculiar in this respect was the catatono-hebephrenic variant.

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Catatonic Schizophrenia

Catatonia is a psychomotor symptom in which patients present with stupor, although catatonic excitement may also present at the other end of the spectrum. Catatonia has been historically associated with schizophrenia although it is also associated with other neuropsychiatric disorders. Find the latest research on catatonic schizophrenia here.

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