Effectiveness of two rehabilitation treatments in the modulation of inflammation during the acute phase in patients with knee prostheses and assessment of the role of the diet in determining post-surgical inflammation.

Journal of Orthopaedics
Sergio RigoniMario Scapin

Abstract

NCT04580069. Total knee arthroplasty is associated with an elevated inflammatory response both at a local and systemic level. The main objective of this study is to demonstrate the effectiveness of lymphatic drainage and connective tissue techniques in modulating systemic inflammation. Another objective is to evaluate the existence, at baseline, of a correlation between the inflammation indices and the level of adherence to the Mediterranean diet. 34 patients were recruited, and divided into three groups. The control group followed the normal rehabilitation protocol. The other two groups were subjected, in addition to the standard treatment, to manual lymphatic drainage treatment or connective tissue techniques. The outcomes were recorded in three stages: upon entering the hospital, 1 week after entry and at follow-up 21 days after surgery. The results of the study showed that both methods, compared with the standard treatment only, positively influenced the final outcomes. In regard to the systemic inflammation, lymphatic drainage and connective techniques showed equal efficacy and similar timing in modulating ESR, while they differ in how they affect CRP. With regard to the local inflammation, the effectiveness of both method...Continue Reading

References

Mar 30, 2001·The Journal of International Medical Research·O BilgenM S Bilgen
Jan 16, 2008·Clinical Orthopaedics and Related Research·Kwan Kyu ParkKyoung Un Park
Jan 13, 2011·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Luckshman BavanJagdeep Nanchahal
Dec 3, 2011·The British Journal of Nutrition·Philip C CalderBrigitte M Winklhofer-Roob
Dec 25, 2013·Lymphatic Research and Biology·Artur SchanderLisa M Hodge
Apr 3, 2015·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Zu Yue DengChen Gang

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

© 2021 Meta ULC. All rights reserved