PMID: 3748569Jan 1, 1986Paper

Effects of 0.1% cyclopentolate or 10% phenylephrine on pupil diameter and accommodation

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
J A MordiW N Charman

Abstract

The mydriatic and cycloplegic effects of either one drop of 0.1% cyclopentolate or two drops of 10% phenylephrine were studied over a period of up to 6 hours after drug instillation, using 5 subjects aged between 25 and 43 years. The extent of mydriasis was determined from the horizontal diameter of the pupil. Dynamic accommodation responses were monitored with an infra-red, continuously recording optometer. Static measurements of the accommodation response/stimulus curve were made with a laser optometer. With either drug, dilation of the pupil occurred more rapidly than recovery of normal pupil diameter. Both drugs caused alterations in the dynamic and static accommodation responses. Response times were generally slowed, and the slope of the accommodation response/stimulus curve and the amplitude of accommodation were reduced. The time course of these changes was broadly similar to that of the pupil dilation. Cyclopentolate hydrochloride was more efficient as a mydriatic but exercised a greater unwanted cycloplegic effect.

Citations

Jul 1, 1989·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·C Schor, D Horner
Jul 1, 1993·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·M RosenfieldB Gilmartin
Apr 1, 1994·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·G GimpelW M Lyle
Jan 15, 2005·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Bin Wang, Kenneth J Ciuffreda
Dec 4, 2012·Indian Journal of Ophthalmology·Samrat SarkarShrikant R Bharadwaj
Jul 15, 2009·The Journal of Emergency Medicine·Matej Polomský, Janet Smereck
Aug 26, 2015·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·W Neil Charman, Gordon Heron
May 16, 2006·Vision Research·Bin WangBalamurali Vasudevan
Jun 6, 2006·Vision Research·Bin WangTrevor Irish
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Oct 23, 2012·Ophthalmology·Takahiro HiraokaTetsuro Oshika
Oct 3, 2002·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·G HeronL S Gray
Mar 1, 1990·Current Eye Research·M RosenfieldN Dattani

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