Effects of a compound Chinese herbal medicine Yixin Jiedu formula on haemodynamic in rats with heart failure of qi-deficiency and blood stasis syndrome

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Chun LiWei Wang

Abstract

To explore the effects of Yixin Jiedu Formula (YXJDF), a compound Chinese herbal medicine, on hemodynamic and B-type natriuretic (BNP) in a rat model of heart failure with qi deficiency and blood stasis syndrome. Moreover, its therapeutic effects in improving the symptoms were also studied. The model of heart failure was established by ligation of left coronary artery in rats. Rats were randomly divided into sham-operated group, model group, YXJDF group and positive control (sodium fosinopril tablet) group. On the second day after the operation, rats in different groups received different treatments. Rats in the YXJDF group were treated with YXJDF (9.33g/kg); rats in the positive control group received solution of sodium fosinopril tablet (1.2mg/kg) and rats in the model and the control groups were given an equal volume of saline, respectively. Drugs were delivered by intragastric administration for 28d. Symptoms such as respiratory rate and red-green-blue value of color of the plantar skin were also collected. Then hemodynamic indexes were evaluated and the levels of plasma BNP were examined by enzyme-linked immunosorbent assay (ELISA) in all groups. After 28d, rats in the YXJDF group and the positive control group were more a...Continue Reading

References

Apr 10, 2003·Mayo Clinic Proceedings·Brian P ShapiroMargaret M Redfield
Feb 16, 2006·Cleveland Clinic Journal of Medicine·James L Januzzi
Apr 24, 2007·Journal of the American College of Cardiology·Patrick JourdainYves Juillière
Jan 20, 2010·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Chang-xun ChenWei-liang Gu
Mar 24, 2010·Archives of Internal Medicine·Pramote PorapakkhamHenry Krum

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