Effects of a mineralized human cancellous bone allograft in regeneration of mandibular Class II furcation defects

Journal of Periodontology
Yi-Pin TsaoHom-Lay Wang

Abstract

A solvent-preserved, mineralized human cancellous bone allograft (MBA) was recently developed. However, its effect in regenerating furcation defects remains to be determined. Hence, the aim of the study is to evaluate the effects of this newly introduced MBA, with and without a bioabsorbable collagen membrane, for the treatment of mandibular class II furcation defects. Thirty subjects with Hamp's Class II buccal or lingual furcation defects in lower molars were randomly assigned to open flap debridement (OFD), MBA, or MBA with a bioabsorbable collagen membrane (guided tissue regeneration [GTR]+MBA) groups. Clinical and defect measurements were obtained at the initial visit and at 6-month reentry surgeries. The data were analyzed for intra- and intergroup comparisons and associations of treatment with probability of clinical improvement. Out of a total of 30 subjects, 27 individuals completed the study. Vertical bone fill (VBF) was -1.6+/-2.1 mm in OFD, 1.9+/-1.4 mm in MBA, and 0.7+/-0.9 mm in GTR+MBA groups. VBF in MBA and GTR + MBA groups was significantly higher than that in the OFD group (P<0.05). Horizontal bone fill (HBF) was 0.2+/-1.7 mm, 1.1+/-0.9 mm, and 1.1+/-0.9 mm for OFD, MBA, and GTR+MBA groups, respectively. Howev...Continue Reading

References

Feb 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·A E PostlethwaiteA H Kang
Aug 1, 1975·Journal of Clinical Periodontology·S E HampJ Lindhe
Aug 1, 1990·Journal of Periodontology·R G CaffesseW Becker
Apr 1, 1989·Journal of Periodontology·L B HelldenJ E Steffensen
Aug 1, 1986·Journal of Periodontology·A D SteinbergJ Lipowski
Apr 1, 1988·Journal of Clinical Periodontology·B GantesJ Egelberg
Jul 1, 1986·Journal of Clinical Periodontology·J GottlowJ Wennström
Nov 1, 1987·Journal of Clinical Periodontology·R PontorieroF Sanavi
Jan 1, 1972·Journal of Periodontology·T J O'LearyJ E Naylor
Feb 1, 1972·Journal of Periodontology·H L Levine, S S Stahl
Nov 1, 1967·Journal of Periodontology·H Löe
Nov 12, 1965·Science·M R Urist
Nov 1, 1994·Journal of Periodontology·H L WangR L MacNeil
Mar 1, 1993·Journal of Periodontology·U ZappaD Case
May 16, 1998·Journal of Clinical Periodontology·G CarnevaleG di Febo
Apr 6, 2001·Journal of Periodontology·P Bunyaratavej, H L Wang
Jan 7, 2003·The Journal of the American Dental Association·Michael S BlockRobert Lytle
Oct 31, 2003·Journal of Periodontology·Gerald M BowersMark A Reynolds

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Citations

Mar 16, 2007·Implant Dentistry·Hom-Lay Wang, Yi-Pin Tsao
Nov 26, 2010·Journal of Periodontology·Bassam Michael KinaiaMonish Bhola
Nov 20, 2012·Journal of Indian Society of Periodontology·Deepti KhannaD Venugopal Naidu
Apr 14, 2015·Periodontology 2000·Mariano SanzSøren Jepsen
Aug 21, 2013·International Journal of Oral and Maxillofacial Surgery·N TovarP G Coelho
Nov 3, 2012·Acta Cirúrgica Brasileira·José Dias da Silva NetoLydia Masako Ferreira
Nov 28, 2013·The Journal of Craniofacial Surgery·Nick TovarPaulo G Coelho

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