Effects of a powered air-purifying respirator intervention on indium exposure reduction and indium related biomarkers among ITO sputter target manufacturing workers

Journal of Occupational and Environmental Hygiene
Hung-Hsin LiuChiung-Yu Peng

Abstract

This study aimed to evaluate the efficacy of powered air-purifying respirators (PAPRs) worn by the workers, and to investigate the effect of this application on exposure and preclinical effects in terms of workplace measuring and biomarker monitoring in ITO sputter target manufacturing plants and workers, respectively. Fifty-four workers were recruited and investigated from 2010-2012, during which PAPRs were provided to on-site workers in September 2011. Each worker completed questionnaires and provided blood and urine samples for analysis of biomarkers of indium exposure and preclinical effects. Area and personal indium air samples were randomly collected from selected worksites and from participants. The penetration percentage of the respirator (concentration inside respirator divided by concentration outside respirator) was 6.6%. Some biomarkers, such as S-In, SOD, GPx, GST, MDA, and TMOM, reflected the decrease in exposure and showed lower levels, after implementation of PAPRs. This study is the first to investigate the efficacy of PAPRs for reducing indium exposure. The measurement results clearly showed that the implementation of PAPRs reduces levels of indium-related biomarkers. These findings have practical applications...Continue Reading

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Citations

Aug 24, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Yu-Chung TsaoJiin-Chyuan John Luo

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Methods Mentioned

BETA
liquid crystal display
scraping
MDA
electrophoresis
enzyme-linked immunosorbent assay

Software Mentioned

PASW Statistics
SPSS

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