Effects of a single exercise bout on insulin sensitivity in black and white individuals

The Journal of Clinical Endocrinology and Metabolism
Rebecca E HassonBarry Braun

Abstract

Previous research suggests non-Hispanic blacks (blacks) are more insulin resistant than non-Hispanic whites (whites). Physical activity can play an important role in reducing insulin resistance. However, it is unknown whether racial differences exist in response to exercise. Therefore, the purpose of this study was to compare metabolic responses to a single bout of exercise in blacks and age-, sex-, and body mass index-matched whites. Whole-body insulin sensitivity, glucose storage, glucose oxidation, and respiratory exchange ratio (RER) were assessed during a hyperinsulinemic-euglycemic clamp in normoglycemic blacks (n = 11) and whites (n = 10). Outcome measures were evaluated in a sedentary control condition and 12 h after treadmill walking at 75% of maximal heart rate for 75 min. In the control condition, there were no differences in insulin sensitivity between blacks and whites (P = 0.54). During the clamp, glucose oxidation and insulin-stimulated RER values were significantly higher in blacks compared with whites (P = 0.04 and P < 0.01, respectively). Despite similar RER values during exercise, RER values at 60, 90, and 120 min after exercise in blacks were also significantly higher compared with whites (P < 0.05). After e...Continue Reading

References

May 1, 1990·The American Journal of Clinical Nutrition·P L Pellett
Aug 1, 1983·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·G W HeathJ O Holloszy
Jul 7, 1999·The American Journal of Clinical Nutrition·C WeyerE Ravussin
Aug 24, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·S B RacetteS Klein
Apr 13, 2004·Journal of Applied Physiology·Scott G GlickmanDonald R Dengel
Aug 6, 2005·Journal of Applied Physiology·Steven E BlackBarry Braun
Jul 27, 2006·The Journal of Clinical Endocrinology and Metabolism·Evan S BerkJeanine B Albu
Oct 17, 2008·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Kaila A HoltzBarry Braun

❮ Previous
Next ❯

Citations

Jun 6, 2012·Journal of Nutrition and Metabolism·Kevin R ShortApril M Teague
Sep 27, 2018·Expert Review of Proteomics·Rikke Kruse, Kurt Højlund
Nov 19, 2013·The Journal of Clinical Endocrinology and Metabolism·Corey A RyndersArthur Weltman
May 13, 2019·European Journal of Applied Physiology·Todd CastleberryVic Ben-Ezra
Aug 14, 2021·Cardiovascular Endocrinology & Metabolism·Fred J DiMenna, Avigdor D Arad

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.