Effects of a single preappointment dose of gabapentin on signs of stress in cats during transportation and veterinary examination

Journal of the American Veterinary Medical Association
Karen A van HaaftenMelissa J Bain

Abstract

OBJECTIVE To determine the effects of oral gabapentin administration prior to veterinary examination on signs of stress in cats. DESIGN Randomized, blinded, crossover clinical trial. ANIMALS 20 healthy pet cats with a history of fractious behavior or signs of stress during veterinary examination. PROCEDURES Cats were scheduled for 2 veterinary visits 1 week apart and randomly assigned to receive a capsule containing 100 mg of gabapentin (13.0 to 29.4 mg/kg [5.9 to 13.4 mg/lb]) or placebo (lactose powder) prior to the first visit and the opposite treatment prior to the second visit. Owners were instructed to administer the assigned capsule orally 90 minutes prior to placing the cat into a carrier and transporting it to the veterinary hospital. Standardized physical examinations and blood pressure readings were performed. Owners assigned a cat stress score during transportation and examination, and the veterinarian assigned a compliance score at the visit. Scores were compared between treatments, controlling for various factors. RESULTS Owner-assessed cat stress scores during transportation and veterinary examination and veterinarian-assessed compliance scores were significantly lower when cats received gabapentin than when they ...Continue Reading

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Citations

Jul 11, 2018·Journal of Feline Medicine and Surgery·Sheilah A RobertsonGregg M Griffenhagen
Aug 4, 2018·Journal of Feline Medicine and Surgery·Pia R QuittLara Matiasek
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Dec 24, 2021·Journal of Feline Medicine and Surgery·Paulo V SteagallSamantha Taylor

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