PMID: 7547716Apr 1, 1995Paper

Effects of a static magnetic field on haemoglobin structure and function

International Journal of Biological Macromolecules
M M AtefM A Fadel

Abstract

The exposure of mice to static magnetic fields (MF) of different strengths (1000-4000 G) for 10 min was studied. The effects of these magnetic fields on the function of haemoglobin (Hb), and its conformational stability, auto-oxidation kinetics, bioenergetics and viscosity, and those of different Hb derivatives were investigated. The fractions and concentrations of the inactive Hb pigments (such as methaemoglobin, carboxyhaemoglobin and sulfohaemoglobin) and the active Hb (in the HbO2 form) were determined using a newly developed multi-component spectrophotometric method. The direct effect of magnetic fields of relatively high strengths (3500 and 4000 G) led to different Hb conformations, accompanied by changes in intermolecular interactions represented by the slope of the eta sp/C = F(C) lines and Huggins' constant K', while no measurable change in the intrinsic viscosity [eta] of Hb was observed. These results indicate a lack of changes in the dimensions and shape of the Hb molecule. Study of the kinetics of oxyhaemoglobin auto-oxidation revealed decreases in the auto-oxidation reaction rate of 2-5.9% and 10-17%, under the effect of static MFs of strengths 1000-2500 G and 3500-4000 G, respectively.

References

Jun 1, 1990·Digestive Diseases and Sciences·R A BakerJ Toouli
Oct 30, 1985·Biochemical and Biophysical Research Communications·J A WatkinsW S Caughey
Jan 15, 1986·Biochemical Pharmacology·D GuillochonD Thomas
Jul 15, 1988·The Science of the Total Environment·J Braven, A S Fisher
Jan 1, 1986·The Japanese Journal of Physiology·S ShimizuS Sakata
Jul 15, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·N Fogh-AndersenP D Wimberley
Jan 1, 1987·International Archives of Occupational and Environmental Health·M SavićD Djulizibarić
Nov 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·O Siggaard-AndersenJ Rem
Nov 20, 1973·Biochemistry·A Mansouri, K H Winterhalter
Feb 18, 1971·The New England Journal of Medicine·L A TrivelliH T Lai
Mar 27, 1981·Biochimica Et Biophysica Acta·K ImaiM Hirano
May 1, 1981·Chemical & Pharmaceutical Bulletin·K KikugawaT Kurechi
Jul 1, 1981·Journal of Clinical Chemistry and Clinical Biochemistry. Zeitschrift Für Klinische Chemie Und Klinische Biochemie·A ZwartW G Zijlstra
May 1, 1959·Psychological Bulletin·A E MAXWELL

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Citations

Nov 19, 2013·Progress in Biophysics and Molecular Biology·Shuguang Yu, Peng Shang
Mar 15, 2001·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·A P AlfanoG T Gillies
Apr 27, 2010·Pakistan Journal of Biological Sciences : PJBS·Mohamed Anwar K Abdelhalim, Sherif Abdelmottaleb Moussa
Sep 12, 2015·Environmental Science and Pollution Research International·Miryam ElferchichiKaren Lambert
Jun 15, 2007·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Yadollah Soleymani ShayestehArash Khojasteh
Sep 7, 2006·Electromagnetic Biology and Medicine·Sihem ChaterKhémais Ben Rhouma
Sep 22, 2009·Archives of Medical Research·Dilek Ulker CakirNuriye Mete
May 20, 2011·Electromagnetic Biology and Medicine·Mohamed A Elblbesy
Apr 25, 2007·Electromagnetic Biology and Medicine·Farong LiQiang Wang
May 16, 2012·Toxicology and Industrial Health·Ozlem Coskun, Selcuk Comlekci
Aug 2, 2005·Biophysical Chemistry·Anna MichnikKatarzyna Michalik
Sep 9, 2020·Ecotoxicology and Environmental Safety·Tatjana TasićSilvio R De Luka

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