PMID: 7734433Jan 1, 1995Paper

Effects of a water-soluble ethylhydroxyethyl cellulose on gut physiology, bacteriology, and bacterial translocation in acute liver failure

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
X WangR Andersson


Bacterial infection and bacteremia are common complications in patients with acute liver failure. Bacterial translocation from the gut has been suggested to be a major cause of bacterial infections in experimental acute liver failure. In the present study, a water-soluble ethylhydroxyethyl cellulose (EHEC) was administered orally 1 and 24 hours prior to 90% hepatectomy in the rat in order to prevent bacterial translocation in experimental acute liver failure induced by subtotal liver resection in the rat. Ninety percent hepatectomy alone resulted in 80 to 100% translocation to mesenteric lymph nodes or blood 2 and 4 hours after operation. There was no translocation in rats undergoing sham operation or 90% hepatectomy with EHEC administration prior to operation (p < .01). Bacterial overgrowth, increased bacterial adherence onto the intestinal surface, and diminished intestinal and mucosal mass were also observed in animals with subtotal liver resection, but not in those administered EHEC. A delayed 2-hour intestinal transit time occurred in both groups receiving subtotal liver resection, with or without oral EHEC. EHEC inhibited bacterial growth and DNA synthesis and altered bacterial surface properties after 1-hour incubation w...Continue Reading


Oct 1, 1978·The American Journal of Clinical Nutrition·A M Connell
Sep 1, 1992·Archives of Surgery·X WangS Bengmark
Feb 1, 1991·Archives of Surgery·C L WellsK J Gillingham
Feb 1, 1991·American Journal of Surgery·A E BarberG T Shires
Mar 11, 1991·Gastroenterology·J A ReillyL F Rikkers
Jan 1, 1990·Molecular Plant-microbe Interactions : MPMI·N K Peters, D P Verma
Mar 1, 1990·World Journal of Surgery·K Offenbartl, S Bengmark
Oct 1, 1990·Annals of Surgery·J W AlexanderS K Ash
Sep 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·J E Kinsella
Jan 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N RolandoR Williams
Aug 1, 1987·Applied and Environmental Microbiology·M C van LoosdrechtA J Zehnder
Mar 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·S A KripkeJ L Rombeau
Aug 1, 1989·The Journal of Surgical Research·N HosodaM Yamamoto
Jun 1, 1988·The British Journal of Surgery·D CranstonJ Collin
May 1, 1985·The American Journal of Clinical Nutrition·G V VahounyM M Cassidy
Sep 1, 1988·Reviews of Infectious Diseases·C L WellsR L Simmons
Feb 1, 1986·Archives of Dermatology·D S Feingold
Aug 1, 1985·The Anatomical Record·M BjerknesS Erlandsen
Mar 1, 1982·Liver·R J WykeR Williams
Jan 1, 1993·The British Journal of Surgery·X D WangS Bengmark
Jan 1, 1993·Scandinavian Journal of Gastroenterology·X D WangS Bengmark
Jan 1, 1993·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·X WangS Bengmark

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