PMID: 7734433Jan 1, 1995Paper

Effects of a water-soluble ethylhydroxyethyl cellulose on gut physiology, bacteriology, and bacterial translocation in acute liver failure

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research
X WangR Andersson

Abstract

Bacterial infection and bacteremia are common complications in patients with acute liver failure. Bacterial translocation from the gut has been suggested to be a major cause of bacterial infections in experimental acute liver failure. In the present study, a water-soluble ethylhydroxyethyl cellulose (EHEC) was administered orally 1 and 24 hours prior to 90% hepatectomy in the rat in order to prevent bacterial translocation in experimental acute liver failure induced by subtotal liver resection in the rat. Ninety percent hepatectomy alone resulted in 80 to 100% translocation to mesenteric lymph nodes or blood 2 and 4 hours after operation. There was no translocation in rats undergoing sham operation or 90% hepatectomy with EHEC administration prior to operation (p < .01). Bacterial overgrowth, increased bacterial adherence onto the intestinal surface, and diminished intestinal and mucosal mass were also observed in animals with subtotal liver resection, but not in those administered EHEC. A delayed 2-hour intestinal transit time occurred in both groups receiving subtotal liver resection, with or without oral EHEC. EHEC inhibited bacterial growth and DNA synthesis and altered bacterial surface properties after 1-hour incubation w...Continue Reading

References

Oct 1, 1978·The American Journal of Clinical Nutrition·A M Connell
Sep 1, 1992·Archives of Surgery·X WangS Bengmark
Feb 1, 1991·Archives of Surgery·C L WellsK J Gillingham
Feb 1, 1991·American Journal of Surgery·A E BarberG T Shires
Mar 11, 1991·Gastroenterology·J A ReillyL F Rikkers
Jan 1, 1990·Molecular Plant-microbe Interactions : MPMI·N K Peters, D P Verma
Mar 1, 1990·World Journal of Surgery·K Offenbartl, S Bengmark
Oct 1, 1990·Annals of Surgery·J W AlexanderS K Ash
Sep 1, 1990·JPEN. Journal of Parenteral and Enteral Nutrition·J E Kinsella
Jan 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N RolandoR Williams
Aug 1, 1987·Applied and Environmental Microbiology·M C van LoosdrechtA J Zehnder
Mar 1, 1989·JPEN. Journal of Parenteral and Enteral Nutrition·S A KripkeJ L Rombeau
Aug 1, 1989·The Journal of Surgical Research·N HosodaM Yamamoto
Jun 1, 1988·The British Journal of Surgery·D CranstonJ Collin
May 1, 1985·The American Journal of Clinical Nutrition·G V VahounyM M Cassidy
Sep 1, 1988·Reviews of Infectious Diseases·C L WellsR L Simmons
Feb 1, 1986·Archives of Dermatology·D S Feingold
Aug 1, 1985·The Anatomical Record·M BjerknesS Erlandsen
Mar 1, 1982·Liver·R J WykeR Williams
Jan 1, 1993·The British Journal of Surgery·X D WangS Bengmark
Jan 1, 1993·Scandinavian Journal of Gastroenterology·X D WangS Bengmark
Jan 1, 1993·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·X WangS Bengmark

❮ Previous
Next ❯

Citations

Mar 8, 2011·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Constantinos NastosNikolaos Arkadopoulos
Aug 7, 2007·Expert Review of Anti-infective Therapy·Paul N Goldwater

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Archives of Allergy and Immunology
Yuriko SuzakiTetsuya Uchida
Journal of Thrombosis and Haemostasis : JTH
J Gitschier
Hepatology Research : the Official Journal of the Japan Society of Hepatology
Konstantinos KalimerisNikolaos Arkadopoulos
© 2021 Meta ULC. All rights reserved