PMID: 6106663Jan 1, 1980Paper

Effects of acute and chronic administration of phencyclidine on tyrosine hydroxylase activity in rat striatum

Journal of Neural Transmission
R C SmithD E Leelavathi

Abstract

Following a single dose of phencyclidine (PCP) striatal tyrosine hydroxylase (TH) activity was decreased 42% 15 min after PCP administration, but returned toward baseline levels by 45 min post-drug. Twenty-four hours after the 30th dose of PCP, TH activity remained depressed when compared to the chronic slaine controls. TH activity was not further depressed 15 or 45 min after the 31st dose of PCP.

References

Aug 1, 1978·Pharmacology, Biochemistry, and Behavior·L D Chait, R L Balster
Dec 1, 1978·European Journal of Pharmacology·R F SchlemmerJ M Davis
Nov 7, 1975·Science·P M GrovesG V Rebec
Apr 15, 1978·European Journal of Pharmacology·R L Balster, L D Chait
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Mar 1, 1959·A.M.A. Archives of Neurology and Psychiatry·E D LUBYR KELLEY

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Citations

Nov 5, 1982·European Journal of Pharmacology·M A Bayorh, I J Kopin
Jan 1, 1988·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·S F AliS C Body
Jan 13, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ikuko MiyazakiNorio Ogawa

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