Effects of acute and chronic hypoxia on acid-base regulation, hematology, ion, and osmoregulation of juvenile American paddlefish

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Daniel L Aboagye, Peter J Allen

Abstract

Despite the increasing prevalence of hypoxia in natural habitats occupied by the American paddlefish, basal bony fish, and ram ventilator, information about its response to hypoxia is scarce. To understand the physiological and biochemical responses of juvenile paddlefish (~150 g) to acute (<24 h) and chronic hypoxia (≥24 h), blood oxygen transport, blood acid-base balance, and metabolic stress were evaluated under four different partial pressures of oxygen [pO2; normoxia (148 mmHg), mild hypoxia (89 mmHg), moderate hypoxia (59 mmHg), and extreme hypoxia (36 mmHg)], all at 21 °C. Arterial blood samples were collected from paddlefish after they had been exposed to treatments for 0.25, 2, 6, 24, and 72 h, and analyzed for hematocrit, pO2, total oxygen content, oxygen saturation, pCO2, pH, hemoglobin, Na+, K+, Ca2+, Cl-, glucose, and lactate. Mild hypoxia only caused a reduction in blood pO2 and oxygen saturation. Both acute and chronic moderate and extreme hypoxia caused a decrease in blood pH, pO2, total oxygen content, plasma Na+, and Cl- at all time points. Acute moderate and extreme hypoxia resulted in an increase in blood pCO2, plasma glucose, lactate, and hematocrit. Chronic exposure to moderate hypoxia resulted in an incre...Continue Reading

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Citations

Feb 5, 2019·Fish Physiology and Biochemistry·Mohsen Abdel-TawwabCaterina Faggio
Feb 21, 2021·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·You-Wu DaiJiong Chen
Apr 1, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Yu-Kun JieLing-Tong Ye
Jun 15, 2021·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Jessica A D LégerDenina B D Simmons
Sep 15, 2021·Fish Physiology and Biochemistry·Livia de Assis PortoGisele Cristina Favero

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