PMID: 1033517Nov 5, 1976Paper

Effects of acute cold exposure on the distribution of cardiac output in the sheep

Pflügers Archiv : European journal of physiology
J R HalesA A Fawcett

Abstract

Conscious adult Merino sheep were studied in a thermoneutral environment and then during cold exposure. Microspheres labelled with 141Ce, 51Cr, 85Sr, and 46Sc were used to measure blood flow (Q) in most tissues of the body. (Microspheres labelled with 125I were found to be unsatisfactory.) Cold exposure which caused a marked decrease in skin surface temperature and mild, continuous shivering but no change in deep body temperature, was associated with mean increases in oxygen consumption, heart rate, and cardiac output (C.O.) of 100%, 62%, and 48%, respectively; blood pressure and total peripheral resistance were unchanged. There was approximately a 6-fold increase in Q in perirenal white adipose tissue, and a 3- to 4-fold increase in muscles of the upper foreleg and hindleg, and the intercostals; myocardial Q also increased significantly. There was a marked decrease in Q in skin of the legs and ears, in the maxillo turbinals and in the nasal mucosa, and a decrease in the total proportion of C.O. passing through arteriovenous anastomoses. Thus, not only did C.O. increase, but there was a redistribution appropriate to meet the challenge with which the animal was confronted.

References

Jan 1, 1975·British Medical Bulletin·G Alexander
Nov 14, 1975·Pflügers Archiv : European journal of physiology·J R HalesJ W Bennett
Nov 1, 1968·British Journal of Pharmacology·G P Lewis, J Matthews
Jan 1, 1974·Physiological Reviews·L B Rowell
Oct 1, 1973·The Journal of Physiology·G AlexanderJ R Hales
Nov 26, 1973·Pflügers Archiv : European journal of physiology·J R Hales
Dec 12, 1973·Pflügers Archiv : European journal of physiology·J R Hales
Jan 1, 1972·Pflügers Archiv : European journal of physiology·W RiedelE Simon
Jan 1, 1966·British Medical Bulletin·D Hull
Feb 1, 1970·The Journal of Physiology·M J Hardman, D Hull
Jul 1, 1968·Canadian Journal of Physiology and Pharmacology·L Jansky, J S Hart
Sep 1, 1968·The Journal of Physiology·G Alexander, D Williams
Mar 1, 1969·Canadian Journal of Physiology and Pharmacology·G E Thompson, D M Jenkinson
Jun 1, 1969·Canadian Journal of Physiology and Pharmacology·A J WebsterF L Hays

Citations

Dec 15, 1978·Pflügers Archiv : European journal of physiology·J R HalesA D Needham
Jul 1, 1984·Pflügers Archiv : European journal of physiology·G Barnas, W Rautenberg
Dec 12, 1977·Pflügers Archiv : European journal of physiology·J R HalesA A Fawcett
Jan 1, 1985·Pharmacology & Therapeutics·C Jessen
Jan 1, 1990·Comparative Biochemistry and Physiology. A, Comparative Physiology·B M WeaverM R Pearson
Mar 1, 1994·Comparative Biochemistry and Physiology. Comparative Physiology·R D Kilgour, P A Williams
Mar 23, 2000·Cardiovascular Research·F W Prinzen, J B Bassingthwaighte
Jun 25, 2014·Journal of Thermal Biology·Thad E WilsonKevin D Monahan
Sep 1, 1983·Journal of Veterinary Pharmacology and Therapeutics·P L ToutainJ D Baggot
Jul 10, 2020·Journal of Applied Physiology·Robert D Hyldahl, Jonathan M Peake
Sep 27, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J B ChambersM E Rashotte
Aug 5, 1998·The American Journal of Physiology·M F Van OosterhoutJ R Hales
Jul 1, 1984·Pflügers Archiv : European journal of physiology·G BarnasW Rautenberg
Jan 1, 1980·Progress in Lipid Research·R G Vernon

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