Effects of Acute Exposure to Endosulfan (Organochlorine Pesticides) on Hematology of African Mud Catfish, Clarias gariepinus (Burchell, 1822)

Bulletin of Environmental Contamination and Toxicology
P E NdimeleS Onuoha

Abstract

Changes in the blood parameters of fingerlings of Clarias gariepinus were investigated after 24 and 96-h of exposures to endosulfan. 180 fingerlings of C. gariepinus [mean weight (10.5±1.3 g); total length (11.2±1.2 cm)] were exposed to five different concentrations (1.00, 2.20, 4.80, 11.00, 23.00 µg/L) of endosulfan and a control for 96 h after being acclimatized for 21 days. After 24 h of exposure, microcytic hypochromic anemia was observed and all erythrocyte profiles tested showed significant variation (p<0.05) among the treatments except thrombocyte and mean corpuscular hemoglobin concentration. Macrocytic hyperchromic anemia was noticed after 96 h of exposure and all the hematological parameters varied significantly (p<0.05) except packed cell volume and red blood cell count. The study shows that endosulfan alters the hematology of C. gariepinus fingerlings. Therefore, awareness on the hazards associated with the use of endosulfan should be intensified and sound sustainable alternatives to endosulfan should be developed.

References

Jan 1, 1986·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·J H van Vuren
Apr 30, 2003·Bulletin of Environmental Contamination and Toxicology·F JenkinsR Madhavi
Jul 26, 2008·Bulletin of Environmental Contamination and Toxicology·Premysl MikulaZdenka Svobodova

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Citations

May 22, 2016·Bulletin of Environmental Contamination and Toxicology·Alina PaunescuMaria Cristina Ponepal
Apr 2, 2016·Archives of Environmental Contamination and Toxicology·Concillia MondePaul J Van den Brink
Aug 14, 2020·Environmental Analysis, Health and Toxicology·Ebenezer I OladokunJoseph C Anikwe

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