Effects of admission glucose level on mortality after subarachnoid hemorrhage: a comparison between short-term and long-term mortality

Journal of the Neurological Sciences
Seung-Hoon LeeByung-Woo Yoon

Abstract

Admission hyperglycemia is associated with poor functional outcomes and risk of death in nondiabetic patients with acute ischemic stroke. However, there is still some debate about the effects of hyperglycemia in subarachnoid hemorrhage (SAH) patients. The purpose of this study was to assess whether the admission glucose level in patients with SAH is associated with short- and/or long-term mortality. A consecutive data set of SAH patients without diabetes was obtained from a prospective multicenter cohort of hemorrhagic stroke patients. The effects of glucose level were examined in relation to short- (30 days) or long-term mortality using Cox regression analysis. To eliminate the short-term effects of glucose level, the long-term effects were analyzed in the patients who survived for more than 30 days. A total of 803 SAH patients were followed up in this study. The 30-day and final mortalities were 7.6% and 12.0%, respectively. Throughout the entire follow-up period, glucose level was found to be significantly associated with final mortality after adjusting for potential confounders (adjusted HR, 1.10; 95% CI, 1.01 to 1.19). Moreover, glucose level was found to be associated with short-term mortality (adjusted HR, 1.15; 95% CI, ...Continue Reading

References

May 1, 1992·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·N ArakiM Reivich
Jun 1, 1991·Italian Journal of Neurological Sciences·G CazzatoL G Iona
Aug 1, 1990·Stroke; a Journal of Cerebral Circulation·A HijdraJ van Gijn
Dec 1, 1993·Journal of Neurosurgery·G LanzinoW Alves
Aug 1, 1993·Stroke; a Journal of Cerebral Circulation·F van KootenP J Koudstaal
Jul 2, 1999·Stroke; a Journal of Cerebral Circulation·C CharpentierM C Laxenaire
Oct 6, 2001·Stroke; a Journal of Cerebral Circulation·S E CapesH C Gerstein
Apr 18, 2002·Journal of the Neurological Sciences·Agnieszka SlowikAndrzej Szczudlik
Mar 8, 2003·Stroke; a Journal of Cerebral Circulation·Salah-Eddine MegherbiUNKNOWN European BIOMED Study of Stroke Care Group
Aug 9, 2003·Stroke; a Journal of Cerebral Circulation·Eun-Chol SongByung-Woo Yoon
Oct 29, 2003·Neurology·S M Dorhout MeesG J E Rinkel
Dec 13, 2005·Stroke; a Journal of Cerebral Circulation·Jennifer A FronteraStephan A Mayer
Jan 11, 2007·Neurology·B W YoonUNKNOWN Acute Brain Bleeding Analysis (ABBA) Study Investigators

❮ Previous
Next ❯

Citations

Aug 19, 2011·Neurocritical Care·Erich SchmutzhardUNKNOWN Participants in the International Multi-Disciplinary Consensus Conference on the Critical care Management of Subarachnoid He
Oct 23, 2012·Critical Care : the Official Journal of the Critical Care Forum·Andreas H KramerDavid A Zygun
Sep 15, 2012·Emergency Medicine Clinics of North America·J Alfredo Caceres, Joshua N Goldstein
Apr 13, 2010·Neurosurgery Clinics of North America·Katja E Wartenberg, Stephan A Mayer
Oct 18, 2012·Clinical Neurology and Neurosurgery·Liheng BianXingquan Zhao
Apr 23, 2019·European Stroke Journal·Blanca FuentesUNKNOWN European Stroke Organisation

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.