Effects of age and body lead burden on CNS function in young children. I. slow cortical potentials

Electroencephalography and Clinical Neurophysiology
D A OttoC N Barton

Abstract

The effects of body Pb burden on slow cortical potentials were studied in 63 children aged 13-75 months. Slow wave (SW) voltage during sensory conditioning varied as a linear function of blood lead (PbB) level. The slope of this function, moreover, changed systematically with age. For children under 5 years of age, SW voltage tended to be positive at low PbBs and to be negative above 30 micrograms/dl. For children over 5 years of age, SW voltage tended to be negative at low PbBs and to be less negative (or positive) above 30 micrograms/dl. These results provide evidence of altered CNS function at the lowest Pb effect level ever reported.

References

Mar 1, 1979·Archives of Environmental Health·O J DavidS Hoffman
Jun 24, 1977·Science·E R JohnE Schwartz
Nov 1, 1976·Archives of Environmental Health·H RoelsJ Van Overschelde
Oct 1, 1972·British Journal of Industrial Medicine·A M Seppäläinen, S Hernberg
Dec 1, 1972·The Journal of Pediatrics·B De la Burdé, M S Choate
Mar 1, 1973·Psychophysiology·W T Roth
Aug 1, 1970·Archives of Environmental Health·S HernbergH Lilius
Oct 1, 1981·Electroencephalography and Clinical Neurophysiology·V A BenignusK J Seiple

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Citations

Aug 1, 1995·American Journal of Industrial Medicine·K MurataS J Liu
Oct 1, 1981·Electroencephalography and Clinical Neurophysiology·V A BenignusK J Seiple
Jan 1, 1986·Physiology & Behavior·W J EngellennerP J Donovick
Dec 1, 1984·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J MartineauG Lelord
Mar 1, 1991·Pediatric Neurology·V C WongC Y Yeung
May 1, 1990·Neurotoxicology and Teratology·J M DavisL D Grant
Sep 2, 1982·The New England Journal of Medicine·J S Lin-Fu
May 1, 1987·Archives of Environmental Health·J Schwartz, D Otto
Dec 1, 1986·Journal of Clinical and Experimental Neuropsychology·D L MolfeseR J Erwin
May 1, 1990·Food Additives and Contaminants·M J Quinn, J C Sherlock
Dec 1, 1995·Environmental Health Perspectives·D C Rice
Nov 1, 1985·Environmental Health Perspectives·G F NordbergT W Clarkson
Apr 1, 1993·Environmental Health Perspectives·L J Folinsbee
May 1, 1988·The Journal of Pediatrics·M ShannonF H Lovejoy
Jan 1, 1988·Journal of Toxicology. Clinical Toxicology·F LilleS Dally
Jan 1, 1984·Annals of the New York Academy of Sciences·D KurtzbergL E Putnam
Oct 1, 1987·Journal of Learning Disabilities·D Fishbein, J Meduski
May 1, 1985·Journal of Learning Disabilities·R W Thatcher, M L Lester
Dec 1, 1986·Toxicology and Industrial Health·W L Marcus
Mar 1, 1983·Psychophysiology·K E MullerV A Benignus
Jan 1, 1988·Critical Reviews in Toxicology·A M Seppäläinen
Jan 1, 1984·Annals of the New York Academy of Sciences·D OttoG Lelord
Jan 1, 1991·Life Sciences·J M Bertoni, P M Sprenkle
Jan 1, 1985·Progress in Neurobiology·G Audesirk

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