PMID: 9442237Jan 27, 1998Paper

Effects of age and location on the biomechanical and biochemical properties of canine tracheal ring cartilage in dogs

American Journal of Veterinary Research
A HamaideK Gardner

Abstract

To evaluate effects of age (immature vs adult) and location along the trachea on the biomechanical properties (via a tensile stress relaxation test) and biochemical properties (Water content and total proteoglycan content) of canine tracheal ring cartilage. Entire trachea from 8 immature and 8 adult dogs. A section of each tracheal ring from 8 immature dogs (6 months old) and 8 adult dogs (2 to 3 years old) was tested biomechanically (maximal stress, equilibrium stress, equilibrium modulus, and percentage of relaxation) and processed for biochemical analysis (water content and total proteoglycan content). Two rings from each trachea were prepared for histologic analysis (H&E or safranin-O staining). Biomechanical and biochemical parameters were not different between cervical and thoracic rings of either age group. Mean maximal stress, equilibrium stress, and equilibrium modulus were significantly higher for adult, compared with immature, dogs. However, percentage of relaxation for adult dogs was significantly lower. Tracheal rings of adult dogs had a significantly higher proteoglycan content and a significantly lower water content than did those of immature dogs. Water content and biomechanical parameters were significantly cor...Continue Reading

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