PMID: 8453191Mar 1, 1993Paper

Effects of age and menopause on bone density of entire skeleton in healthy and osteoporotic women

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
R Nuti, G Martini

Abstract

We studied 885 women to evaluate the effects of age and menopause on bone mineral density (BMD) in both healthy and postmenopausal osteoporotic subjects. The study cohort consisted of 161 healthy premenopausal women (age range 25-54 years), 357 healthy postmenopausal women (35-85 years) and 367 osteoporotic women (41-87 years). Total body and regional (spine, trunk, pelvis, arms, legs) BMD were measured with a dual-energy X-ray (DXA) device (Lunar DPX). Premenopausal BMD values remained essentially unchanged until the first half of the fourth decade, when they decreased. BMD values in both healthy postmenopausal and osteoporotic women were significantly lower than premenopausal values, and continued to decrease statistically after the onset of menopause. The highest Z-score (0.96 +/- 0.92) was found for total body BMD. Higher T-score values were found in osteoporotic than in normal postmenopausal women. In both healthy and osteoporotic postmenopausal women the best fits for BMD changes in total body, spine, trunk, arms and legs were obtained with the natural logarithm of years since menopause; only the pelvis BMD decreased linearly. Multiple regression analysis indicated that postmenopausal BMD changes in both normal and osteop...Continue Reading

References

Aug 11, 1975·The Journal of Clinical Investigation·D M SmithC C Johnston
Sep 1, 1991·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·F DuboeufP J Meunier
Jul 1, 1991·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·R NutiV Turchetti
Nov 1, 1990·Metabolism: Clinical and Experimental·J F AloiaS H Cohn
Jan 1, 1990·The Journal of Clinical Endocrinology and Metabolism·B E NordinH A Morris
Mar 1, 1989·Calcified Tissue International·R MazessJ Hanson
Apr 1, 1989·Calcified Tissue International·S A ErikssonJ U Lindgren
Apr 1, 1989·Scandinavian Journal of Clinical and Laboratory Investigation·A GotfredsenC Christiansen
Dec 1, 1989·Scandinavian Journal of Clinical and Laboratory Investigation·A GotfredsenC Christiansen
Jan 1, 1989·Annals of Biomedical Engineering·R B MazessM Ettinger
Jul 1, 1989·Proceedings of the Society for Experimental Biology and Medicine·R B Mazess, H S Barden
Jun 1, 1989·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J W DavisJ M Vogel
May 1, 1986·Calcified Tissue International·T Hansson, B Roos
Sep 1, 1986·Calcified Tissue International·K ThomsenC Christiansen
Oct 1, 1988·European Journal of Clinical Investigation·L Nilas, C Christiansen
Oct 1, 1988·Bone and Mineral·C RibotR Guiraud
Jun 1, 1988·The Journal of Clinical Investigation·S L HuiC C Johnston
Dec 1, 1987·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J C GallagherA Moy
Jun 26, 1986·The New England Journal of Medicine·B L Riggs, L J Melton
Oct 1, 1987·The Journal of Clinical Endocrinology and Metabolism·L Nilas, C Christiansen
Aug 1, 1986·American Journal of Epidemiology·L J MeltonB L Riggs

❮ Previous
Next ❯

Citations

Nov 1, 1995·Calcified Tissue International·R NutiC Gennari
Apr 1, 1995·Calcified Tissue International·A BagurC Mautalen
Jan 1, 1995·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·W YuH K Genant
Sep 4, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H YanH-W Deng
Dec 3, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A C LookerJ McGowan
Jun 2, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M PirroE Mannarino
Jul 1, 1995·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·K MizunoY Tomoda
Mar 19, 2003·Clinical Nuclear Medicine·Mustafa Yildiz, Baha Oral
Jun 1, 1997·The Journal of Obstetrics and Gynaecology Research·Y InoY Tomoda
Mar 26, 2002·Climacteric : the Journal of the International Menopause Society·E ErtungealpA Gezer
Mar 23, 2002·Climacteric : the Journal of the International Menopause Society·M SanadaK Ohama
Feb 3, 2007·Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen·A SchmittE Cunha
Feb 26, 1999·Seminars in Ultrasound, CT, and MR·S GramppH Imhof
Oct 23, 2013·HIV Clinical Trials·Jeannie S HuangUNKNOWN Aids Clinical Trials Group A5142 Study Team
Apr 23, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Leonid KalichmanGregory Livshits
May 23, 2000·American Journal of Physical Medicine & Rehabilitation·E Gosfield, F J Bonner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.