PMID: 24353685Dec 20, 2013Paper

Effects of alcohol on the morphological and structural changes in oral mucosa

Pakistan Journal of Medical Sciences
Lin Feng, Lili Wang

Abstract

To investigate the morphological and structural changes of oral mucosa under the influence of alcohol. Sixty male and female specimens (42 males and 18 females) who died of chronic alcoholism were selected in this study. The specimens (5-7 mm) were sliced by the morphological-histological detection method, and stained by the HE and Spielmeyer (myelin staining) protocols respectively. Then five immune peroxidase chemical reaction tests were performed. 10% of the tissue sections had epithelial hyperplasia points with hyperkeratosis and acanthosis. 90% of the sections had epithelial atrophy points with different degrees of damage, and had moderate infiltration of lymphocytes-macrophages in the basal oral mucosa simultaneously. For the tissue sections of patients who died of cardiovascular diseases with a history of alcoholism, about a half showed that extensive necrotic points were observed in different parts of oral mucosa, accompanied by a secondary infection. Approximately 15% of the sections had more dense and homogeneous necrotic tissues with microbial colonization, and the necrotic focus of 5% of the sections was located above the epithelial tissue, which was not distinctively different from other tissues. 48% of the section...Continue Reading

Citations

Sep 10, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Mahdieh-Sadat MoosaviYaser Fathi
Jan 26, 2020·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Majdy IdreesCamile S Farah
Jan 16, 2020·International Journal of Molecular Sciences·Joan OlivaYutaka Niihara
Oct 30, 2019·Anti-cancer Agents in Medicinal Chemistry·Nooshin MohtashamFarnaz Mohajertehran
Apr 23, 2021·Archives of Oral Biology·Merlyn Dos Santos MaidanaFlavio Manoel Rodrigues da Silva Júnior

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