Jan 1, 1976

Effects of Alfatesine (ct 1341) on cerebral blood flow and metabolism in man. Global and regional changes

Annales de l'anesthésiologie française
A M RenouJ M Caille

Abstract

The effects of Alfatesine on local cerebral blood flow and on cerebral oxygen consumption were studied in 5 normal subjects and in 6 patients suffering from diffuse vascular repercussion of cerebral distress. There is a 75 p. 100 fall in cerebral blood flow in the gray substance and a parallel fall in oxygen consumption. At rest, the caracteristic anaesthetic action modifies the caracteristical distribution of blood flows in the cortex. A relative hyperemia appears in the area of the central sulcus. Those focal changes could not be found in the group of pathogical patients.

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Mentioned in this Paper

Metabolic Process, Cellular
Cerebral Blood Flow Imaging
Dioxygen
Cortex Bone Disorders
Adrenal Cortex Diseases
Blood Vessel
Brain
Blood Flow
Anesthesia, Intravenous
Entire Central Sulcus

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