Effects of Alkaline-Reduced Drinking Water on Irritable Bowel Syndrome with Diarrhea: A Randomized Double-Blind, Placebo-Controlled Pilot Study

Evidence-based Complementary and Alternative Medicine : ECAM
Dong Woo ShinDong Ho Lee

Abstract

The purpose of this study was to investigate whether the ingestion of alkaline-reduced water (ARW) is helpful in improving the symptoms of diarrhea-predominant irritable bowel syndrome (IBS). Twenty-seven patients (male, 25.9%; mean, 41.7 years old) with diarrhea-predominant IBS were randomly allocated to two groups. For eight weeks, the ARW group (n = 13) ingested at least 2 liters/day of ARW, while the control group (n = 14) ingested placebo water. IBS symptom scores (quality-of-life, abdominal pain/discomfort), stool form, and frequency were assessed before and after treatment via questionnaires. Eight patients (61.5%) in the ARW group and six patients (42.9%) in the control group indicated that their symptoms had improved in more than four out of the eight weeks of treatment (p = 0.449). The IBS quality-of-life score significantly improved from 57.2 to 30.8 in the ARW group; this improvement was significantly greater than the slight improvement from 48.7 to 42.2 observed in the control group (p = 0.029). The abdominal pain score improved from 1.8 to 0.9 in the ARW group and from 1.8 to 1.1 in the control group, with no significant group difference (p = 0.232). Drinking ARW for eight weeks improves the quality of life in pat...Continue Reading

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Citations

Jan 25, 2020·PloS One·Asma Salari-MoghaddamPeyman Adibi
Dec 13, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Takaaki YahiroMasafumi Inomata
Jun 13, 2020·Journal of Food Biochemistry·Harini RangarajanDuggonahalli Veeresh Chidanand
Sep 23, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Wade BillingsAndrea Shin

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