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Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets

Naunyn-Schmiedeberg's Archives of Pharmacology

Jan 1, 1975

Uwe Panten

PMID: 1687

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Abstract

In perifused isolated pancreatic islets alpha-ketoisocaproic acid (KIC) or alpha-ketocaproic acid (KC) induced a high insulin secretion rate and a steep increase of the fluorescence of reduced pyridine pyridine nucleotides [NAD(P)H] which fell again to almost prestimulatory levels 6 min...read more

Mentioned in this Paper

Phenylpyruvate
alpha-ketoisocaproic acid
Pyruvate Measurement
NADP
NADH
Acids
Valerates
Islets of Langerhans
Metazoa
Propionic Acids
Paper Details
References
    • References21
    • Citations16
    • References21
    • Citations16
  • Effects of alpha-ketomonocarboxylic acids upon insulin secretion and metabolism of isolated pancreatic islets

    Naunyn-Schmiedeberg's Archives of Pharmacology

    Jan 1, 1975

    Uwe Panten

    PMID: 1687

    DOI:

    Abstract

    In perifused isolated pancreatic islets alpha-ketoisocaproic acid (KIC) or alpha-ketocaproic acid (KC) induced a high insulin secretion rate and a steep increase of the fluorescence of reduced pyridine pyridine nucleotides [NAD(P)H] which fell again to almost prestimulatory levels 6 min...read more

    Mentioned in this Paper

    Phenylpyruvate
    alpha-ketoisocaproic acid
    Pyruvate Measurement
    NADP
    NADH

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    Paper Details
    References
    • References21
    • Citations16
    • References21
    • Citations16
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