PMID: 9420682Mar 1, 1994Paper

Effects of altered left ventricular geometry on quantitative technetium 99m sestamibi defect size in humans: perfusion imaging during coronary angioplasty

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
H L HaronianF J Wackers

Abstract

Serial myocardial perfusion imaging is used to assess exercise-induced myocardial ischemia and myocardial risk area, salvage, and viability in patients with myocardial infarction. In an experimental animal model it has been shown that abnormal regional wall motion and altered left ventricular geometry can produce apparent perfusion defects independent of changes in blood flow. The effects of regional alteration in ventricular geometry on perfusion images in humans are not defined. The purpose of our investigation was to evaluate quantitatively the effect of altered left ventricular geometry on myocardial perfusion imaging with technetium 99m sestamibi during coronary angioplasty. Nine patients with normal baseline left ventricular function referred for angioplasty of the left anterior descending coronary artery were studied. 99mTc sestamibi was administered intravenously before angioplasty. Baseline planar electrocardiographic-gated imaging was performed. Imaging was repeated in the catheterization laboratory during angioplasty vessel occlusion when altered left ventricular geometry was produced and again later after angioplasty. Summed static, end-systolic, and end-diastolic images were generated from the electrocardiographic-...Continue Reading

References

Aug 1, 1991·The American Journal of Cardiology·R A KlonerC E Ruiz
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Jan 1, 1985·Seminars in Nuclear Medicine·F J WackersJ P Clements
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Citations

Jun 1, 1995·Journal of the American College of Cardiology·D M GallikM S Verani
May 10, 2005·The American Journal of Cardiology·Barry Lewis Zaret
Jan 13, 2004·Journal of Electrocardiology·Lawrence M TitleB Milan Horácek
Oct 22, 2003·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Carlo TraniAttilio Maseri
Apr 1, 1996·Clinical Nuclear Medicine·B B ChinA Alavi
Aug 24, 2020·JACC. Cardiovascular Imaging·Vasken DilsizianCharles A Herzog

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