Effects of ambient temperature on myocardial infarction: A systematic review and meta-analysis
Abstract
Previous studies have suggested that ambient temperature is associated with the mortality and morbidity of myocardial infarction (MI) although consistency among these investigations is lacking. We performed a meta-analysis to investigate the relationship between ambient temperature and MI. The PubMed, Web of Science, and China National Knowledge Infrastructure databases were searched back to August 31, 2017. The pooled estimates for different temperature exposures were calculated using a random-effects model. The Cochran's Q test and coefficient of inconsistency (I2) were used to evaluate heterogeneity, and the Egger's test was used to assess publication bias. The exposure-response relationship of temperature-MI mortality or hospitalization was modeled using random-effects meta-regression. A total of 30 papers were included in the review, and 23 studies were included in the meta-analysis. The pooled estimates for the relationship between temperature and the relative risk of MI hospitalization was 1.016 (95% confidence interval [CI]: 1.004-1.028) for a 1 °C increase and 1.014 (95% CI: 1.004-1.024) for a 1 °C decrease. The pooled estimate of MI mortality was 1.639 (95% CI: 1.087-2.470) for a heat wave. The heterogeneity was signi...Continue Reading
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