PMID: 6111991Apr 1, 1980Paper

Effects of amyl nitrite on left ventricular systole times in normal subjects and those with aortic valvulopathy. Echophonomechanographic assessment

Archivio per le scienze mediche
G Gullace, G Ribecca

Abstract

Echophonomechanographic traces showing systole times, the circumferential restriction time, and the ejection fraction were compared in normal subjects, those with aortic stenosis, and those with aortic insufficiency under basal conditions and after 45" inhalation of amyl nitrite. Significant changes in these parameters after stimulation were noted in the normal subjects only, while the differences between the two groups of patients and the controls were also statistically significant under both experimental conditions. The fact that the diseased subjects did not reach the values noted in the controls is attributed to a latent contractility defect under basal conditions that is rendered evident by amyl nitrite. Stress is laid on the usefulness of the drug in the detection of left ventricle myocardial contraction defects via the analysis of ventricular function.

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.