PMID: 8458821Feb 1, 1993Paper

Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and postexercise

Journal of Applied Physiology
M M KanterJ O Holloszy

Abstract

We studied the effects of ingesting an antioxidant vitamin mixture for 6 wk on breath pentane and serum malondialdehyde (MDA) levels before and after exercise. Twenty young (mean age 25.0 +/- 2.9 yr) healthy males were randomly assigned to either an antioxidant vitamin group (daily doses of 592 mg of alpha-tocopherol equivalents, 1,000 mg of ascorbic acid, and 30 mg of beta-carotene) or a placebo group. Exercise consisted of 30 min of treadmill running at 60% of maximal O2 consumption (VO2max) followed by 5 min of running at a pace that elicited approximately 90% of VO2max. Blood and breath samples were collected immediately after the two exercise bouts. The antioxidant supplement did not prevent the exercise-induced increase in lipid peroxidation, as reflected by the rate of pentane production and the increase in serum MDA concentration. However, ingestion of the antioxidant vitamins did result in significantly lower resting and postexercise levels of expired pentane and serum MDA. We conclude that taking ascorbate, alpha-tocopherol, and beta-carotene in the amounts used in this study serves to lower markers of lipid peroxidation at rest and after exercise but does not prevent the exercise-induced increase in oxidative stress.

Citations

Aug 1, 1996·Journal of Sports Sciences·H E PoulsenK Vistisen
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·Z RadákH Ohno
Feb 25, 1998·Medicine and Science in Sports and Exercise·J M McBrideW Sebastianelli
May 8, 1998·The Proceedings of the Nutrition Society·M Kanter
Oct 12, 1999·Journal of Applied Physiology·L C LandsA A Smountas
Dec 22, 1999·The American Journal of Physiology·L M HeunksP N Dekhuijzen
May 15, 2001·Clinical Chemistry and Laboratory Medicine : CCLM·G AndicanG Burçak
Nov 16, 2001·Sports Medicine·C K Sen
Apr 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·Shlomit ChevionYoram Epstein
Jan 30, 2004·The British Journal of Nutrition·Stéphane PalazzettiIrène Margaritis
Mar 9, 2005·Annals of the New York Academy of Sciences·M J JacksonA McArdle
Jun 21, 2005·Annals of the New York Academy of Sciences·Jen-Fang LiuMei-Chieh Hsu
Jul 26, 2005·American Journal of Respiratory and Critical Care Medicine·Evi M MerckenEmiel F M Wouters
Dec 31, 2005·Journal of Applied Physiology·Christian P FischerBente K Pedersen
Feb 21, 2006·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Tongjian YouMichael J McKenzie
Dec 13, 2005·Sports Medicine·Niels B J VollaardChris E Cooper
Dec 14, 2007·The Tohoku Journal of Experimental Medicine·Y Gül OzkayaPiraye Yargiçoğlu
May 27, 2008·Journal of the International Society of Sports Nutrition·Claudio C ZoppiDenise V Macedo
Oct 17, 2008·Physiological Reviews·Scott K Powers, Malcolm J Jackson
Aug 20, 2009·Clinical Science·William D-C ManMichael I Polkey
Dec 11, 2013·Sports Medicine·Jeanick Brisswalter, Julien Louis
Jul 3, 2016·European Journal of Applied Physiology·Iiro A VälimäkiTommi J Vasankari
Mar 1, 2014·Biophysics Reviews·Juan C CalderónCarlo Caputo
Nov 1, 1994·Intensive Care Medicine·G CamusM Lamy
Jun 1, 1997·Free Radical Research·K OkamuraY Sugawa-Katayama
Dec 16, 1998·Journal of the American College of Nutrition·J T VenkatramanG Fernandes
Aug 1, 1997·Medicine and Science in Sports and Exercise·D A LeafT J Barstow
Apr 3, 2003·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Carole GroussardArlette Gratas-Delamarche
Jun 16, 2006·Medicine and Science in Sports and Exercise·Richard J BloomerMichael J McKenzie
Mar 16, 2012·The Cochrane Database of Systematic Reviews·Goran BjelakovicChristian Gluud
Dec 20, 2011·European Addiction Research·Maarten O KokJos W R Twisk
Apr 19, 2013·Experimental and Therapeutic Medicine·Zichao ChenChuan Long Zhang
Dec 21, 2012·Cellular and Molecular Life Sciences : CMLS·Paola VendittiSergio Di Meo
Jan 9, 1998·Research Quarterly for Exercise and Sport·H M Alessio, E R Blasi
Jul 27, 2001·The American Journal of Clinical Nutrition·B E WendlandJ P Allard

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