PMID: 51812Jan 1, 1975Paper

Effects of antibiotics on the life cycle of Neurospora crassa

Folia Microbiologica
V BetinaJ Spisiaková

Abstract

Some antibiotics and synthetic inhibitors affect, in several ways, the life cycle of Neurospora crassa (germination of conidia leads to myceliar growth leads to formation of conidia). Bikaverin, cyanein, scopathricin and phenethyl alcohol retard the germination of conidia, without inhibiting it completely. 5-Fluorouracil, ramihyphin A and zygosporin A (cytochalasin D) do not inhibit the germination. Bikaverin brings about a thickening of the hyphae of growing mycelium. Ramihyphin A, cyanein, scopathricin and zygosporin A stimulate the ramification of hyphae while 5-fluorouracil and phenethyl alcohol do not affect the myceliar morphology apart from their inhibitory effect on growth. Actinomycin D, 5-fluorouracil, cycloheximide, ramihyphin A and partially also sodium iodoacetate inhibit to a different degree the photoinduced formation of conidia. The inhibition by 5-fluorouracil is very conspicuous when the agent is present during the photoinduction but considerably weaker when it is applied 2 h after the photoinduction.

References

Jan 1, 1975·Folia Microbiologica·H BaráthováP Nemec
Jan 1, 1974·Folia Microbiologica·Z BaráthP Nemec
Jan 1, 1972·Journal of Bacteriology·W D Nunn, B E Tropp
Jan 1, 1973·Zeitschrift für allgemeine Mikrobiologie·V Betina, D Miceková
Jan 1, 1971·Journal of the Chemical Society. Perkin Transactions 1·J W CornforthD Park
Sep 15, 1969·Experientia·G Combépine, J Chervet
Jan 1, 1970·Molecular & General Genetics : MGG·A S Bhagwat, P R Mahadevan
Jun 1, 1967·Developmental Biology·J Gressel, E Galun

❮ Previous
Next ❯

Citations

Jan 1, 1976·Folia Microbiologica·H Baráthová, V Betina
Apr 9, 2010·Applied Microbiology and Biotechnology·M Carmen LimónJavier Avalos
Feb 11, 2005·Antonie van Leeuwenhoek·Felipe Alcántara-SánchezJosé Ruiz-Herrera
Jan 1, 1976·Folia Microbiologica·V Betina, SpiĭakoviJ

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.