Effects of azadirachtin on the development and mortality of Lutzomyia longipalpis larvae (Diptera: Psychodidae: Phlebotominae)

Journal of Medical Entomology
Claudia Alves Andrade CoelhoElizabeth F Rangel

Abstract

The effects of azadirachtin A added to the standard diet on the development, mortality, and metamorphosis of Lutzomyia longipalpis Lutz & Neiva, 1912 were studied. Concentrations of 0.1, 1.0, and 10.0 microg of azadirachtin/mg of diet significantly increased larval mortality in comparison with nontreated insects. Concentrations 0.1 and 1.0 microg blocked the molt of larvae, which remained as third instars until the end of the experiment. The 10 microg/mg concentration resulted in greater molt inhibition. In this group, all insects stopped their development as second instars. Simultaneous addition of ecdysone (1 microg/mg) to the standard diet containing azadirachtin counteracted the effects of azadirachtin on mortality and inhibition of ecdysis. These results indicate that azadirachtin is a potent growth inhibitor of L. longipalpis.

References

Jan 1, 1991·Memórias do Instituto Oswaldo Cruz·E S GarciaP Azambuja
Jan 1, 1987·Memórias do Instituto Oswaldo Cruz·E S GarciaP de Azambuja
Dec 10, 1999·Memórias do Instituto Oswaldo Cruz·N A SouzaE F Rangel
Aug 11, 2004·Toxicon : Official Journal of the International Society on Toxinology·E S Garcia, P Azambuja

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Citations

Mar 5, 2011·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Alon Warburg, Roy Faiman

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