Effects of Bariatric Surgery on Outcomes of Patients With Acute Pancreatitis

Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Somashekar G KrishnaDarwin L Conwell

Abstract

The prevalence of obesity and number of patients undergoing bariatric surgery are increasing. Obesity has adverse effects in patients with acute pancreatitis (AP). We investigated whether bariatric surgery affects outcomes of patients with AP. We performed a retrospective study, collecting data from the US Nationwide Inpatient Sample (2007-2011) on all adult inpatients (≥18 years) with a principal diagnosis of AP (n = 1,342,681). We compared primary clinical outcomes (mortality, acute kidney injury, and respiratory failure) and secondary outcomes related to healthcare resources (hospital stay and charges) among patient groups using univariate and multivariate analyses. We performed a propensity score-matched analysis to compare outcomes of patients with versus without bariatric surgery. Of patients admitted to the hospital with a principal diagnosis of AP, 14,332 (1.07%) had undergone bariatric surgery. The number of patients that underwent bariatric surgery doubled, from 1801 in 2007 to 3928 in 2011 (P < .001). AP in patients that had undergone bariatric surgery was most frequently associated with gallstones. Multivariate analysis associated prior bariatric surgery with decreased mortality (odds ratio, 0.41; 95% confidence int...Continue Reading

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Citations

Nov 14, 2016·Gastroenterology Clinics of North America·Zobeida Cruz-MonserrateSomashekar G Krishna
Aug 29, 2019·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Ilma Carla de Souza PorcelliSandra Mara Maciel
Jul 19, 2017·Current Opinion in Gastroenterology·Biswajit KhatuaVijay P Singh
Feb 23, 2020·Journal of Women's Health·Hind A BeydounAlan B Zonderman
Jul 7, 2019·BMC Surgery·Kiran Chandni Baran, Maurits de Brauw
Feb 15, 2020·Obesity Surgery·Paul Thomas KrönerPrabhleen Chahal

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