Effects of bone mineral density of the lumbar spine and prevalent vertebral fractures on the risk of immobility.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Masataka ShirakiShiro Tanaka

Abstract

To clarify the contribution of osteoporosis to future immobilization, a prospective observational study was carried out on Japanese postmenopausal women. The prevalence of low bone mineral density (BMD) and vertebral fracture were independent risks for future immobilization. Immobilization by hip fracture requires more medical care and higher costs. Osteoporosis increases the risk of hip fracture, but there is little data linking osteoporosis and immobilization in postmenopausal Japanese women. The study participants consisted of postmenopausal ambulatory volunteers. Baseline information such as BMD, prevalent fractures, comorbidities, pain in the body, and variables were obtained from 1993, and time course of occurrence of immobilization was observed until 2008. A total of 1,312 participants were enrolled and were observed for a total of 6.7 +/- 4.1 years. A total of 75 subjects suffered immobilization. In multivariate analysis to calculate the Cox's hazard ratio of baseline parameters for immobilization, four independent variables were observed: age (hazard ratio, 1.52 [95% CI, 1.29 to 1.80], p = 0.000), pain in the body (2.54 [1.42 to 4.89, p = 0.001]), low BMD (1.83 [1.10 to 3.13, p = 0.020]), and dementia (3.58 [91.80 to 6...Continue Reading

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Citations

Jan 12, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·K-P KuetN F A Peel
Jun 25, 2013·Calcified Tissue International·Tatsuhiko KurodaMasataka Shiraki
Aug 21, 2013·Journal of Bone and Mineral Metabolism·Shiro TanakaMasataka Shiraki
Apr 24, 2012·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Tatsuhiko KurodaShiro Tanaka
Jan 13, 2016·Journal of Bone and Mineral Metabolism·Tomohiko UranoSatoshi Inoue
Jan 28, 2014·Clinical Therapeutics·Hiroaki OhtaUNKNOWN Adequate Treatment of Osteoporosis (A-TOP) Research Group
Mar 19, 2016·Journal of Cellular Biochemistry·Kenta YamamotoOsam Mazda
Dec 14, 2017·Journal of Bone and Mineral Metabolism·Tomohiko UranoSatoshi Inoue
Sep 5, 2013·Annals of Laboratory Medicine·Erkan CureDavut Keskin
Jul 19, 2018·Journal of Bone and Mineral Metabolism·Yukari UemuraUNKNOWN Adequate Treatment of Osteoporosis (A-TOP) research group
Jan 7, 2020·Journal of Nutritional Science and Vitaminology·Shoji KashiwabaraMasataka Shiraki
Dec 7, 2018·Japanese Journal of Radiology·Shunsuke KameiTsuyoshi Tajima

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