Effects of bright light on sleepiness, melatonin, and 25-hydroxyvitamin D(3) in winter seasonal affective disorder

Biological Psychiatry
T PartonenJ Lönnqvist

Abstract

Sixteen patients with winter seasonal affective disorder and 13 healthy controls were exposed to 3300 lx of cool-white fluorescent light for either 1 hour or 15 min in the morning for 2 weeks during the winter. Subjective sleepiness, melatonin concentration in saliva, and serum 25-hydroxyvitamin D(3) concentration were measured before and after the 2-week trial as well as the following summer when the patients were well. There were no significant differences in the baseline values between the patients and healthy subjects. No significant differences in the outcome measures were observed in the patients or the controls in the two groups of each after the trial. The exposure to bright light resulted in a significant decrease in subjective sleepiness early in the evening in the patients but not in the control subjects. The reduction of depressive symptoms was associated with the decrease in subjective sleepiness but not with the changes in the melatonin or vitamin D concentrations.

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Citations

Jan 7, 2004·Journal of Affective Disorders·Zoltán SzabóZoltán Janka
Aug 14, 2009·Nutrition Reviews·Elizabeth R Bertone-Johnson
Aug 4, 2011·Neuropsychobiology·Gerald PailSiegfried Kasper
Jan 26, 2011·Journal of Psychosocial Nursing and Mental Health Services·Robert H Howland
May 11, 2010·Issues in Mental Health Nursing·Sue PenckoferCarol Estwing Ferrans
Jan 6, 2010·The Physician and Sportsmedicine·Robert H Howland
Aug 31, 2010·Neuroscience and Biobehavioral Reviews·Joanna L Workman, Randy J Nelson
Jul 27, 2018·Expert Opinion on Pharmacotherapy·Olivia CoolsBernard Sabbe
Sep 2, 2008·Journal of Midwifery & Women's Health·Pamela K Murphy, Carol L Wagner
May 2, 2003·Chronobiology International·Andres Magnusson, Diane Boivin
Nov 5, 2003·International Journal of Circumpolar Health·Trond Bratlid, Björn Wahlund

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