Effects of Ca and H2O2 added to RPMI on the fretting corrosion of Ti6Al4V

Journal of Biomedical Materials Research
A MontagueJ Payer

Abstract

Titanium and its alloys have demonstrated considerable success in various surgical procedures including orthopedic, dental, and cardiovascular surgery. However, particulate debris from corrosion and wear is present in a considerable quantity in tissue local to the implant. This study evaluated the effect of Ca, since it is present in both serum and bone, and H2O2, since it is produced through local inflammation, on the amount of titanium release. Four sets of Ti6Al4V plates and Ti6Al4V screws were used. Each set was designated to one of four solutions: RPMI (cell culture growth media), RPMI with CaCl2, RPMI with CaCO3, and RPMI with H2O2. A fretter was used to cause corrosion by creating micromotion between two screws and a two-hole plate of Ti6Al4V. After fretting for 72 h, weight loss of the plate and screws and the amount of Ti and vanadium (V) in solution was used to assess the amount of fretting corrosion which had occurred. Results of weight loss and Ti in solution indicated that the presence of H2O2 increased the amount of particulate debris produced in RPMI as compared with RPMI alone. The addition of CaCl2 to RPMI also increased both weight loss and Ti in solution compared with RPMI alone. The addition of CaCO2, howeve...Continue Reading

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Citations

Nov 26, 1999·Journal of Biomedical Materials Research·Y MuT Hanawa
Mar 10, 2001·Journal of Biomedical Materials Research·J A Hendry, R M Pilliar
Feb 22, 2007·Journal of Biomedical Materials Research. Part a·Ken'ichi YokoyamaJun'ichi Sakai
Mar 12, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nadim James HallabJoshua J Jacobs
Mar 11, 2020·Advanced Science·Shanoob BalachandranMichael Herbig
Nov 8, 2020·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Simona RadiceMarkus A Wimmer

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